Results 131 to 140 of about 1,131,712 (326)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Legislative Effectiveness: The legislative performance of house representatives of the 16th Philippine Congress

open access: yesDiversitas Journal
Policymakers’ legislative performances guide constituents for informed electoral choices. However, the lack of empirical inquiry on the legislative effectiveness of the members of the House of Representatives in the Philippines subjected constituents to
Joanna Marie Baroman
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

The Parapolitical Path to Parliament: Former Political Support Staff as Parliamentary Members

open access: yesPolitics and Governance
In Western parliamentary democracies, a growing number of MPs have worked as special advisers, political assistants, and parliamentary aides before their election as members of parliament.
Anchrit Wille, Mark Bovens
doaj   +1 more source

PERAN HUMAS SETJEN DPR RI DALAM UPAYA MENCIPTAKAN CITRA POSITIF MELALUI PELAYANAN INFORMASI PUBLIK [PDF]

open access: yes, 2017
Media is one of society reference used to know the information about legislative institution, which is Indonesian House of Representatives (DPR RI). However, news saw the number of negative and from results of a survey of trust an agency the house of ...
Adam , Yolanda
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Dean Logan\u27s Blog: Alums in the Legislature and Scholarship Winners Feted at Annual Meeting [PDF]

open access: yes, 2009
The Roger Williams Law Alumni Association (LAA) held its annual meeting in conjunction with the Annual Meeting of the RI Bar Association. The event offered an opportunity to salute the RWU Law graduates who serve in the Rhode Island Legislature: Senators
Roger Williams University School of Law
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Laiklikle İlgili Maddelerin 1961 Anayasası’nda Yer Alış Süreci ve Müzakereleri

open access: yesAkademik İncelemeler Dergisi, 2014
27 Mayıs 1960 Askeri Müdahalesi’nden hemen sonra yeni bir anayasanın yapılması, ivedilikle ele alınması gereken meselelerin başında gelmektedir. İstanbul Komisyonu ve Ankara Komisyonu’nca ayrı ayrı anayasa tasarıları hazırlanmıştır.
Ensar Yılmaz
doaj  

Ideology, Shirking, and the Incumbency Advantage in the U.S. House of Representatives [PDF]

open access: yes
This paper examines how the incumbency advantage is related to ideological voting or legislative shirking that causes the incumbents to diverge from the preference of the median voter using aggregate data for the U.S.
Pavel Yakovlev
core  

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