Results 31 to 40 of about 61,083 (286)
Jurnal Ilmiah Pendidikan Pancasila dan Kewarganegaraan, 2021 This study aimed to analyze the judges' considerations in the Constitutional Court Decision Number 16/PUU-XVI/2018 regarding the provisions of Article 245 paragraph (1) of Law Number 2 of 2018, and to analyze the legal consequences of the Constitutional ...
Hasyimi Pradana
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Cogent EducationThis study aims to provide a critical examination of how English as a Second Language (ESL) teachers in primary classrooms in Malaysia utilise the phonics approach when teaching reading.
Azyan Shafee +2 more
doaj +1 more source
Refinement of the crystal structure of (9,10-triptyceno)-25-crown-7, C34H40O7, measured at 173 K
Zeitschrift für Kristallographie - New Crystal Structures, 2002 C34H40O7, monoclinic, P121/n1(No. 14), a = 12.115(2) Å, b = 15.747(1)Å, c = 15.225(2) Å, β = 97.642(7)°,V = 2878.8 Å3, Z = 4, Rgt(F) = 0.046, wRref(F2) = 0.126, T = 173 K.
Bryan J. C. +3 more
doaj +1 more source
Politika: Jurnal Ilmu Politik, 2013 In the reform era that demands a lot of changes, some incumbent legislators still adorned the face of House of Representatives of Kupang City. This was because the incumbent legislator already well known by electorate and there were no regulation before ...
VERONIKA VERONIKA
doaj +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Key Texas Senate and House water committee chairmen discuss water issues of the 85th Legislature
Texas Water Journal, 2017 Editor-in-Chief’s note: In every odd-numbered year, the Texas Legislature convenes in regular session for 140 days. With this in mind, the Texas Water Journal invited Senator Charles Perry, Chairman of the Senate Agriculture, Water & Rural Affairs ...
Sen. Charles Perry, Rep. Lyle Larson
doaj