Results 51 to 60 of about 61,083 (286)
Jurnal Sistem dan Manajemen Industri, 2017 Public satisfaction can be achieved if the government apparatus directly involved in the service, can understand and appreciate and wish to perform excellent service.
Rizal Sarifuddin
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Transparansi dan Partisipasi Publik dalam Rekrutmen Calon Hakim Konstitusi
Jurnal Konstitusi, 2016 Recruitment is not an arena of “hazing” and the addition of bureaucracy but a forum to explore the nature of integrity, capability, and independence of the candidates for constitutional judges.
Winda Wijayanti +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Commentary: Fresh, Clean Water for Texans Now and for Generations to Come
Texas Water Journal, 2021 Editor-in-Chief's Note: The Texas Water Journal invited Texas state Representative Tracy O. King, incoming chair of the House of Representatives Committee on Natural Resources, to share his thoughts on what is ahead for the Natural Resources Committee ...
Tracy King
doaj
Political Limits to the Processing of Policy Problems
Politics and Governance, 2013 This contribution addresses political limits to the processing of policy problems in the United States. Our foci are the forces that limit policymakers' attention to different aspects of problems and how this affects the prospects for problem resolution.
Peter J. May +2 more
doaj +1 more source
Identifying hidden coalitions in the US House of Representatives by optimally partitioning signed networks based on generalized balance. [PDF]
Sci Rep, 2021 Aref S, Neal ZP.
europepmc +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source