Results 51 to 60 of about 1,131,712 (326)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

An exploration of teachers’ practices related to using the phonics approach in Malaysian ESL classrooms

Cogent Education
This study aims to provide a critical examination of how English as a Second Language (ESL) teachers in primary classrooms in Malaysia utilise the phonics approach when teaching reading.
Azyan Shafee, Mohd Syafiq Aiman Mat Noor, Zachary Farouk Chai   +2 more
doaj   +1 more source

Refinement of the crystal structure of (9,10-triptyceno)-25-crown-7, C34H40O7, measured at 173 K

Zeitschrift für Kristallographie - New Crystal Structures, 2002
C34H40O7, monoclinic, P121/n1(No. 14), a = 12.115(2) Å, b = 15.747(1)Å, c = 15.225(2) Å, β = 97.642(7)°,V = 2878.8 Å3, Z = 4, Rgt(F) = 0.046, wRref(F2) = 0.126, T = 173 K.
Bryan J. C., Gakh A. A., Sachleben R. A., Hay B. P.   +3 more
doaj   +1 more source

PEMASARAN POLITIK LEGISLATIF PETAHANA DALAM MEMENANGKAN PEMILU ANGGOTA DPRD KOTA KUPANG PROVINSI NUSA TENGGARA TIMUR TAHUN 2009 (Kajian Strategi Politik dan Bauran Produk Politik)

Politika: Jurnal Ilmu Politik, 2013
In the reform era that demands a lot of changes, some incumbent legislators still adorned the face of House of Representatives of Kupang City. This was because the incumbent legislator already well known by electorate and there were no regulation before ...
VERONIKA VERONIKA
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Responding to chemical weapons violations in Syria: legal, health, and humanitarian recommendations

Conflict and Health, 2018
Background The repeated use of prohibited chemical weapons in the Syrian conflict poses serious health, humanitarian, and security threats to civilians, healthcare personnel, and first responders. Moreover, the use of chemical weapons constitutes a clear
Julia Brooks, Timothy B. Erickson, Stephanie Kayden, Raul Ruiz, Stephen Wilkinson, Frederick M. Burkle   +5 more
doaj   +1 more source

Relation of House of Representatives / Regiomal Peoples's Representative Assembly with Role of Political Parties in the Era of Reform in Indonesia [PDF]

, 2018
The idea to highlight and expose the dualism and impartiality of parliament members, either regionally and / or at national level, against Reviews their play jobs, functions, and roles as the members of any given political party was the first that Came ...
Tungga, B. (Benjamin), Wartoyo, F. X. (Francis)   +1 more
core  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Key Texas Senate and House water committee chairmen discuss water issues of the 85th Legislature

Texas Water Journal, 2017
Editor-in-Chief’s note: In every odd-numbered year, the Texas Legislature convenes in regular session for 140 days. With this in mind, the Texas Water Journal invited Senator Charles Perry, Chairman of the Senate Agriculture, Water & Rural Affairs ...
Sen. Charles Perry, Rep. Lyle Larson
doaj  

Confirmation of Nelson A. Rockefeller as Vice President of the United States [PDF]

, 1974
Report issued by House Committee on the Judiciary following its hearings on the nomination of Nelson Rockefeller to be the 41st Vice President of the United States. President Gerald Ford had nominated Rockefeller pursuant to Section 2 of the Twenty-Fifth
Committee on the Judiciary. House of Representatives. United States.
core   +1 more source