Results 121 to 130 of about 2,631,521 (295)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Household budgets and women's incomes [PDF]

open access: yes, 1980
African Studies Center Working Paper No. 28While explaining proposed studies of aspects of "household economics" to prospective informants in two different African societies, I have been advised very quickly that "Among us, a man and his wife do not ...
Guyer, Jane I.
core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

The relationship between household consumption expenditure and various factors

open access: yesAgricultural and Food Science, 1967
The purpose of this study has been to elucidate the relationship between various factors and household consumption expenditure. The data, collected by households, are from the rural consumption investigation carried out in 1959/60.
Maire Honkanen
doaj  

The Anti-Flyaway/Frizz Effect by Inducing the α-Helical Structure Transition of Hair

open access: yesCosmetics
In order to reduce chronic hair flyaways/frizz, both reducing and oxidizing agents have to be used, leaving aside the hair damage issues. This study presents changes in hair morphology caused by treatment with a shampoo containing only reducing agents ...
Sang-Hun Song   +2 more
doaj   +1 more source

Expenditure as proxy for UK household emissions? Comparing three estimation methods

open access: yes, 2013
Due to a lack of emissions data at the household level, studies examining the relationship between UK household CO2 emissions and household characteristics currently rely on expenditure surveys to estimate emissions.
Buchs, Milena, Schnepf, Sylke V.
core  

Gamified budgeting for managing household finances [PDF]

open access: yes, 2017
The current UK economic climate is leading households into debt. The rising cost of living and inflation are resulting in households struggling with financial management. This has implications on the quality of life and economic mobility.
Butt , Prins, Sievenpiper , Michael
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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