Results 151 to 160 of about 958,686 (317)

Noncooperative household consumption with caring [PDF]

open access: yes
We present a household consumption model that accounts for caring household members, while allowing for noncooperative behavior in decisions on public goods.
Bram DE ROCK   +2 more
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Mali Household Surveys for Agricultural Biodiversity Assessment

open access: yes
To identify and quantify the number of all plant and animal species (domesticated and wild) and within each species, the number of types/varieties/breeds at the household-level that are: (a) grown on farm and home garden, or collected from the wild; (b ...
Vodouhe, R.   +4 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Household Production Theory and Models [PDF]

open access: yes
 The chapter focuses on household production theory and models for non-agricultural households, largely in developed countries.  The objectives of the paper are: (1) to present several types of microeconomic models of household decision making and ...
Wallace E. Huffman
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Study of the jealousy effects on mental health from the perspective of Islam and Psychology

open access: yesپژوهش در دین و سلامت, 2016
For downloading the full-text of this article please click here. Background and Objectives: Islam considers to health, in all its dimensions including biology, psychology, society and spirituality, As far as the believer is introduced as a person with ...
Shahabadin Zolfaghari   +2 more
doaj  

Continuous Household Survey, 2008-2009

open access: yes, 2009
copyright UK Data Service and data collection copyright owner.The Continuous Household Survey (CHS) is one of the largest continuous surveys carried out in Northern Ireland.
Northern Ireland Statistics and Research Agency, Central Survey Unit
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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