Results 71 to 80 of about 3,219,282 (342)
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Efficacy of SGPP2 Modulation-Mediated Materials in Ameliorating Facial Wrinkles and Pore Sagging
Current Issues in Molecular BiologySkin aging is a complex process with internal and external factors. Recent studies have suggested that enlargement and elongation of skin pores may be early signs of aging in addition to wrinkles and loss of elasticity.
Juhyun Kim +3 more
doaj +1 more source
Tooth wear and cleaning effect of an abrasive-free dentifrice
Journal of Dental Sciences, 2018 Background/purpose: To evaluate the degree of wear on human teeth and the cleaning effect of abrasive-free dentifrice. A sodium pyrophosphate and cellulose-containing abrasive-free dentifrice and calcium carbonate-containing control dentifrice were ...
Jae-Hyun Ahn +3 more
doaj +1 more source
New Zealand regions, 1986-2001: Household and families, and their dwellings [PDF]
, 2005 Household structures and patterns of home ownership can have important implications for the wellbeing of populations. This paper explores regional differences in Household Structure and Home ownership for the period 1986 to 2001.
Baxendine, Sandra +3 more
core +1 more source
BMJ Global Health, 2019 Objective Progress towards equitable and sufficient water has primarily been measured by population-level data on water availability. However, higher-resolution measures of water accessibility, adequacy, reliability and safety (ie, water insecurity) are ...
S. Young +9 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Linking household access to food and social capital typologies in Phalombe District, Malawi [PDF]
, 2023 Ailish Craig +4 more
openalex +1 more source
Household energy isn't all stoves [PDF]
, 1998 When people talk about 'household energy', most people automatically think of stoves. A lot of attention has been paid to improving stoves to make them more energy efficient and to reduce their pollution. This is one side of the 'stoves' approach, whilst
Clancy, J.S.
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
CellsNicotinamide adenine dinucleotide (NAD+) is indispensable for the regulation of biological metabolism. Previous studies have revealed its role in aging and degenerative diseases, while crucially showing that supplementation with NAD+ or its precursors ...
Seongsu Kang +5 more
doaj +1 more source