Non-clinical outcomes of antiretroviral therapy for HIV/AIDS in developing countries: a systematic literature review [PDF]
, 2010 The impacts of antiretroviral therapy on quality of life, mental health, labor productivity, and economic wellbeing for people living with HIV/AIDS in developing countries are only beginning to be measured.
Beard, Jennifer +2 more
core +1 more source
Accounting for the U.S. Earnings and Wealth Inequality [PDF]
, 2003 Publicad
Castañeda, Ana +2 more
core +2 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Energy, Poverty, and Health in Climate Change: A Comprehensive Review of an Emerging Literature
Frontiers in Public Health, 2019 Household energy is increasingly vital for maintaining good health. Unaffordable and inadequate household energy presents adverse consequences that are amplified by poverty and a changing climate.
Sonal Jessel +2 more
doaj +1 more source
DNA methylation and socioeconomic status in a Mexican-American birth cohort. [PDF]
, 2018 Background: Maternal social environmental stressors during pregnancy are associated with adverse birth and child developmental outcomes, and epigenetics has been proposed as a possible mechanism for such relationships.
Coker, Eric +4 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
PLoS Neglected Tropical Diseases, 2018 Over 200,000 new cases of leprosy are detected each year, of which approximately 7% are associated with grade-2 disabilities (G2Ds). For achieving leprosy elimination, one of the main challenges will be targeting higher risk groups within endemic ...
Julia Moreira Pescarini +9 more
doaj +1 more source
Resilience in Caregivers of Partners With Young Onset Dementia: A Concept Analysis [PDF]
, 2018 Introduction: Over 200,000 Americans diagnosed with young onset dementia (YOD), dementia diagnosed prior to age 65, are cared for by family members. This can be costly to caregivers’physical and psychological health. Some adapt well to the caregiver role
Bekhet, Abir K., Kobiske, Karie R.
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Partner and Household Factors Associated with Breastfeeding Practice: A Systematic Review
Jurnal Info KesehatanThe role of partner and family in breastfeeding practice is still rare. Previous studies were more likely to discuss the impact of infant and mother factors. This study aimed to examine the role of partner and family factors associated with breastfeeding
Supriatin Supriatin +3 more
doaj +1 more source