Results 41 to 50 of about 73,962 (261)

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Incorporating Responsiveness to Marketing Efforts in Brand Choice Modeling

open access: yesEconometrics, 2014
We put forward a brand choice model with unobserved heterogeneity that concerns responsiveness to marketing efforts. We introduce two latent segments of households.
Dennis Fok   +2 more
doaj   +1 more source

The role of responsive heterogeneity in sub-Saharan smallholder farming sustainability: socio-economic and biophysical determinants of mineral and organic fertilizers used in South Western Burkina Faso

open access: yesInternational Journal of Agricultural Sustainability, 2023
Sustainable soil nutrient management (SNM) is important for improving soil resources and food security in sub-Saharan African countries. Inherent livelihood diversity may lead to differences in household behavior in the adoption of SNM practices, thus ...
Boundia Alexandre Thiombiano   +2 more
doaj   +1 more source

Risk attitudes and household consumption behavior: Evidence from China

open access: yesFrontiers in Public Health, 2022
Risk attitude is a vital component of public mental health. Thus, the public should be guided to fully comprehend risks to improve public mental health.
Xin Xie, Zefeng Tong, Shulin Xu
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters   +17 more
wiley   +1 more source

The impacts of non-farming income on rural household energy choices: Empirical evidence from China

open access: yesFrontiers in Psychology, 2022
This study uses data from the China Family Panel Studies to analyze the possible impact of non-farming income on household energy choices. We use ordinary least squares and instrumental variable estimation methods to investigate the causal effect of non ...
Gang Peng   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The impact of natural disasters on rural household wealth: Micro evidence from China

open access: yesFrontiers in Environmental Science, 2022
Examining the factors that influence rural households’ wealth facilitates enhancing poor households’ happiness, improving their overall welfare, and narrowing the wealth gap between different households.
Shaoyong Wu   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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