Results 101 to 110 of about 1,360,924 (312)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

No. 07: Household Food Security and Access to Medical Care in Maputo, Mozambique [PDF]

, 2017
The relationship between household access to medical care and food security is a potentially circuitous and challenging relationship to model. This discussion paper uses multiple modelling techniques to determine the quality of the relationships between ...
McCordic, Cameron
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Group-based financial institutions for the rural poor in Bangladesh: an institutional- and household-level analysis [PDF]

Table of Contents: Tables, Figures, Foreword, Acknowledgments, and Summary; 1. Introduction; 2. Determinants of the Placement and Outreach of Group-Based Financial Institutions:A County-Level Analysis; 3.
Ahmed, Akhter U., Rashid, Shahidur, Sharma, Manohar, Zeller, Manfred   +3 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Consumer Food Choices as a Reflection of Concerns about Nutritional Attributes [PDF]

Economic growth changed household food consumption patterns in the Republic of Korea. Consumer survey data were used to identify concerns about fat, saturated fat, sodium, sugar, calories and protein consumption.
Florkowski, Wojciech J., Hwang, Sojin, Lee, In-Kyu   +2 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Hydrogen Micro-Systems: Households’ Preferences and Economic Futility

Energies
This study examines the potential market for residential hydrogen systems in light of the trends towards digitalisation and environmental awareness. Based on a survey of 350 participants, the results indicate that although energy experts are sceptical ...
Anna-Lena Klingler, Julian Dörr
doaj   +1 more source

Multilevel modelling of refusal and noncontact nonresponse in household surveys: evidence from six UK government surveys

, 2007
This paper analyses household unit nonresponse and interviewer effects in six major UK government surveys using a multilevel multinomial modelling approach. The models are guided by current conceptual frameworks and theories of survey participation.
Durrant, Gabriele B., Steele, Fiona
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source