Results 121 to 130 of about 414,008 (316)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Oral Health Status and Oral Hygiene Behavior of Nicobarese Tribes of Car Nicobar Island, India: A Population-based Survey

Journal of Indian Association of Public Health Dentistry
Background: Oral health is a crucial indicator of overall health and well-being. Despite significant medical advancement, the majority of India’s vulnerable populations still struggle with poor oral hygiene and oral health. Therefore, utilizing the World
Rehnuma Parvez, Avijit Roy, Jawahar Ramasamy, Nimisha Sivanandan, Alwin Vins, Harpreet Kaur, Kannan Thiruvengadam, Nagarajan Muruganandam   +7 more
doaj   +1 more source

Predicting Intensification on the Brazilian Agricultural Frontier: Combining Evidence from Lab-In-The-Field Experiments and Household Surveys

Land, 2019
The expansion of crop agriculture onto low productivity cattle pastures in the agricultural frontier of Brazil is a form of agricultural intensification that can help to contribute to global food and climate goals.
Arthur Bragança, Avery Simon Cohn
doaj   +1 more source

Continuous Household Survey, 2006-2007 [PDF]

, 2008
copyright UK Data Service and data collection copyright owner.The Continuous Household Survey (CHS) is one of the largest continuous surveys carried out in Northern Ireland.
Northern Ireland Statistics and Research Agency, Central Survey Unit
core  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Backyard Poultry Farming Among Urban Poor Households in Bangladesh: Production Capacity and Potential Contribution to Food Security

Urban Science
This study aimed to examine the potential influence of backyard poultry farming, which can be readily established in urban and peri-urban environments, on the production capacity of backyard poultry and its potential contribution to food security among ...
Sayaka Ushimaru, A.K.M. Kanak Pervez, Akira Ishida   +2 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Determinants of household saving behaviour in Ghana

Cogent Economics & Finance
Developing countries generally exhibit low ‘saving’ (flow concept) and ‘savings’ (stock concept) rates. The factors underlying household positive or negative saving behaviours in developed and developing countries are not new in the macroeconomic ...
Anthony Amoah, Carlos Kokuvi Tetteh, Noble Osei-Bonsu, Paragon Pomeyie, Godson Ahiabor, George Hughes, Ignanpin Kwabenabu, Benjamin Otchere-Ankrah   +7 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source