Results 131 to 140 of about 1,373,952 (311)
How important are household demographic characteristics to explain private car use patterns? A multilevel approach to Austrian data [PDF]
Private car use is one of the major contributors to pollution in industrialised countries. It is therefore important to understand the factors that determine the demand for car use.
Alexia Fürnkranz-Prskawetz +2 more
core
U.S. Household Savings for Retirement in 2010 [PDF]
, 2013 [Excerpt] This report provides data on a variety of household wealth measures in 2010 from the Federal Reserve’s triennial Survey of Consumer Finances. Although the amount of retirement assets is the primary focus of the report, other measures of wealth (
Topoleski, John J
core +3 more sources
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Gender Labor Income Shares and Human Capital Investment in the Republic of Congo [PDF]
This paper uses a recent, nationally representative household survey for the Republic of Congo—the 2005 ECOM (Enquête Congolaise auprès des Ménages) survey—to test the unitary model of household consumption.
Backiny-Yetna, Prospere, Wodon, Quentin
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
DO HOUSEHOLDS FULLY SHARE RISK? EVIDENCE FROM GHANA [PDF]
Intrahousehold analyses provide new insights into how households make economic decisions. Much of the work in economics has traditionally treated the household as a single economic actor, but a number of studies are providing evidence that the dynamics ...
Doss, Cheryl R.
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Impact of Children on Household Savings in the Philippines [PDF]
Household savings are important indicators of family welfare, not only in terms of a household's investment and income generation prospects, but also, and perhaps more importantly--given pervasive borrowing constraints and limited social security ...
Orbeta, Aniceto Jr. C.
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source