Results 101 to 110 of about 414,008 (316)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Integrated Household Survey, April 2009 - March 2010 [PDF]

open access: yes, 2010
copyright UK Data Service and data collection copyright owner.The Integrated Household Survey (IHS), which ran from 2009-2014, was a composite survey combining questions asked on a number of social surveys conducted by the Office for National Statistics (
Office for National Statistics, Social Survey Division
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Community-mobilized soil and water conservation and farmers' preferences for mitigating land degradation

open access: yesEnvironmental Research Communications
Various soil and water conservation (SWC) practices have been constructed through campaign-based integrated watershed management in Ethiopia since 2011.
Hailu Kendie Addis   +5 more
doaj   +1 more source

[Selection within households in health surveys].

open access: yesRevista de saude publica, 2014
To compare the efficiency and accuracy of sampling designs including and excluding the sampling of individuals within sampled households in health surveys.From a population survey conducted in Baixada Santista Metropolitan Area, SP, Southeastern Brazil, lowlands between 2006 and 2007, 1,000 samples were drawn for each design and estimates for people ...
Alves, Maria Cecilia Goi Porto   +3 more
openaire   +2 more sources

Integrated Household Survey, January - December, 2011 [PDF]

open access: yes, 2012
copyright UK Data Service and data collection copyright owner.The Integrated Household Survey (IHS), which ran from 2009-2014, was a composite survey combining questions asked on a number of social surveys conducted by the Office for National Statistics (
Office for National Statistics, Social Survey Division
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

A Comparison of Tablet-Based and Paper-Based Survey Data Collection in Conservation Projects

open access: yesSocial Sciences, 2014
There is growing use of household surveys by conservation organizations as they seek to measure the social impacts of conservation initiatives, especially in developing countries.
Craig Leisher
doaj   +1 more source

Continuous Household Survey, 1999-2000 [PDF]

open access: yes, 2001
copyright UK Data Service and data collection copyright owner.The Continuous Household Survey (CHS) is one of the largest continuous surveys carried out in Northern Ireland.
Northern Ireland Statistics and Research Agency, Central Survey Unit
core  

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