Results 181 to 190 of about 414,597 (316)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Disparities and barriers to life-course vaccination in Ethiopia: Evidence from a household survey. [PDF]

Hum Vaccin Immunother
Assefa GM, Tarekegn Damtew M, Negash K, Mulugeta B, Wgebriel A, Denekew B, Argaw MD, Semahegn A, Teferi M, Awell T, Solomon S, Shimelis Biru K, Kinfu Tilahun F, Lakew Y, Mihret M, Wondarad Y, Aniefiok Uwah A, Stulz V, Desalegn Muluneh M.   +18 more
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Adverse childhood experiences, resilience and mental health among young people aged 16-29 years in Nepal: a population-based household survey (2025). [PDF]

Lancet Reg Health Southeast Asia
Thapa S, Ross N, Giri S, Ahmed KY, Bhattarai S, Fogden DG, Basnet A, Allan J.   +7 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Survey data on household finance and consumption - research summary and policy use [PDF]

The first part of this paper provides a brief survey of the recent literature that employs survey data on household finance and consumption. Given the breadth of the topic, it focuses on issues that are particularly relevant for policy, namely i) wealth ...
The Eurosystem Household Finance and Consumption Network
core  

Psychometric evaluation of the Kessler 10 measure of psychosocial distress using the 2022 South African population-based household survey. [PDF]

Curr Psychol
Chamane S, Mabaso M, Sewpaul R, Makola L, Jooste S, Moyo S, Mchunu N, Balakrishna Y, Zungu N, Shisana O, Zuma K.   +10 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Prevalence and Patterns of Non-Medical Gabapentinoid Use in a General Population Sample: Findings From the Australian National Drug Strategy Household Survey. [PDF]

Drug Alcohol Rev
McNeilage AG, Xia T, Murnion B, Ashton-James CE, Nielsen S.   +4 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source