Results 191 to 200 of about 414,008 (316)

Is publicly funded health insurance associated with healthcare utilisation and financial protection in India? Evidence from a cross-sectional household survey (CAMS 2022-2023). [PDF]

BMJ Open
Bonu S, Bhushan I.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

The Malaria Vaccine Programme Evaluation in Kenya: results of a baseline household survey prior to the introduction of the RTS,S/AS01 vaccine. [PDF]

Malar J
Westercamp N, Nyangau I, Kwambai TK, Seda B, Akach D, Okanda I, Marube E, Siambe P, Radiro E, Wafula F, Ondiegi B, Shah MP, Seffren V, Moore KA, Fogelson A, Milligan P, Kariuki S, Samuels AM.   +17 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Household survey on prevalence and risk factors for obesity in owned cats from Central Brazil. [PDF]

PLoS One
Silva DC, Porsani MYH, da Cruz AD, Pereira EF, Dos Santos KJG, Minasi LB, Nunes VA, da Cruz AS, Teixeira FA.   +8 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Assessment of a gridded population sample frame for a household survey of refugee populations in Uganda, 2021. [PDF]

Int J Health Geogr
Farley SM, Delgado S, McCracken S, Thomson DR, Chen Q, Reid G, Baptista S, Biraro S, Kabala A, Mulindwa H, Okimait D, Mugisha V, Chung H, Gianetti B, Sendagala S, Nel J, Currie D, West CA, Matovu CH, Nyakoojo R, Kasozi J, Mumbere H, Kirungi W, Musinguzi J, Hoos D, El-Sadr WM.   +25 more
europepmc   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

E-cigarette use and associated factors among adolescents and young adults in northern Thailand: evidence from a population-based household survey. [PDF]

Front Public Health
Oo MZ, Kaewkamthong P, Kaewserm T, Thaikla K.   +3 more
europepmc   +1 more source