Results 191 to 200 of about 414,597 (316)

Is publicly funded health insurance associated with healthcare utilisation and financial protection in India? Evidence from a cross-sectional household survey (CAMS 2022-2023). [PDF]

BMJ Open
Bonu S, Bhushan I.
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The Malaria Vaccine Programme Evaluation in Kenya: results of a baseline household survey prior to the introduction of the RTS,S/AS01 vaccine. [PDF]

Malar J
Westercamp N, Nyangau I, Kwambai TK, Seda B, Akach D, Okanda I, Marube E, Siambe P, Radiro E, Wafula F, Ondiegi B, Shah MP, Seffren V, Moore KA, Fogelson A, Milligan P, Kariuki S, Samuels AM.   +17 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Household survey on prevalence and risk factors for obesity in owned cats from Central Brazil. [PDF]

PLoS One
Silva DC, Porsani MYH, da Cruz AD, Pereira EF, Dos Santos KJG, Minasi LB, Nunes VA, da Cruz AS, Teixeira FA.   +8 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Assessment of a gridded population sample frame for a household survey of refugee populations in Uganda, 2021. [PDF]

Int J Health Geogr
Farley SM, Delgado S, McCracken S, Thomson DR, Chen Q, Reid G, Baptista S, Biraro S, Kabala A, Mulindwa H, Okimait D, Mugisha V, Chung H, Gianetti B, Sendagala S, Nel J, Currie D, West CA, Matovu CH, Nyakoojo R, Kasozi J, Mumbere H, Kirungi W, Musinguzi J, Hoos D, El-Sadr WM.   +25 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

E-cigarette use and associated factors among adolescents and young adults in northern Thailand: evidence from a population-based household survey. [PDF]

Front Public Health
Oo MZ, Kaewkamthong P, Kaewserm T, Thaikla K.   +3 more
europepmc   +1 more source