Results 211 to 220 of about 414,008 (316)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Correction: Accessibility and quality of care for adults with hypertension in rural Burkina Faso: Results from a cross-sectional household survey. [PDF]

PLOS Glob Public Health
Lacey S, Odland ML, Sié A, Harling G, Bärnighausen T, Geldsetzer P, Hirschhorn LR, Davies JI.   +7 more
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Prevalence of protein, lysine, and tryptophan inadequacy and their relation to stunting among Malawian under five children: evidence from the 2019/20 Integrated Household Survey. [PDF]

Front Nutr
Sinkhonde KM, Pangapanga-Phiri I, Osman G, Kalimbira AA.   +3 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Clustering of hypertension and clustering of diabetes at the household level and variations in disease awareness within households in India: findings from a nationally representative household survey. [PDF]

BMJ Glob Health
Pedgaonkar S, Kumar S, Meitei WB, Chaudhary A, Singh A, Singh A.   +5 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The Malaria Vaccine Implementation Programme study area in Ghana: results of a household survey prior to the introduction of the RTS,S/AS01 vaccine. [PDF]

Malar J
Welaga P, Gyan T, Koram K, Hodgson A, Odei-Lartey E, Agbokey F, Gyaase S, Awini E, Adu-Gyasi D, Amenuvegbe GK, Dadzie D, Adam AR, Hammond J, Sarfo A, Nuhu AR, Peprah PT, Twumwaa L, Boateng E, Snell P, Fogelson A, Okine RNA, Hamel MJ, Milligan P, Moore KA, Binka FN, Afari EA, Asante KP.   +26 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Achieving universal health coverage with disability inclusion: a household survey analyzing healthcare access and national health insurance utilization for individuals with disabilities in Indonesia. [PDF]

BMC Health Serv Res
Fanda RB, Muhartini T, Eryani IS, Listyadewi S, Nugrahaeni A, Kurniawan MF, Padmawati RS.   +6 more
europepmc   +1 more source