Results 91 to 100 of about 1,570,129 (332)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The direct and indirect costs associated with food hypersensitivity in households: A study in the Netherlands, Poland, and Spain

open access: yesApstract: Applied Studies in Agribusiness and Commerce, 2016
Background: Recent studies show that food hypersensitivity, such as food allergy or food intolerance, has the potential to affect direct, indirect and intangible economic costs experienced by individuals and their families.
Jantine Voordouw   +17 more
doaj   +1 more source

Factors Affecting the Utilisation of Improved Ventilated Latrines Among Communities in Mtwara Rural District, Tanzania. [PDF]

open access: yes, 2012
The Tanzania government, working in partnership with other stakeholders implemented a community-based project aimed at increasing access to clean and safe water basic sanitation and promotion of personal hygiene in Mtwara Rural District.
Ilako, Festus   +6 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Weatherization Assistance and Low-Income Households [PDF]

open access: yes, 2007
Weatherization is one of the most efficient affordable housing tools available to communities and residents. Weatherization is defined as the practice of protecting a building from the elements (such as sunlight, precipitation and wind) and modifying the
Giessert, Constance
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Evaluation of relationship between banks lending activities and the economies in Baltic countries

open access: yesCopernican Journal of Finance & Accounting, 2016
Banks are financial institutions that are part of each country financial system. One of the banks’ core businesses is lending activity, which includes the lending activity to households, non-financial corporations and other financial institutions ...
Aušrinė Lakštutienė   +1 more
doaj  

Sources and intensity of access to agricultural information technologies by smallholder farmers: evidence from Northwest Ethiopia

open access: yesFrontiers in Sustainable Food Systems
Agriculture is a key sector in many African economies, making access to accurate agricultural information vital for boosting productivity. This study investigated the factors influencing smallholder farmers’ access to agricultural information in the East
Zebenay Shitaye   +8 more
doaj   +1 more source

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