Results 121 to 130 of about 1,390,260 (283)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Housing Deprivation Among Polish Households: Prevalence and Associated Factors

open access: yesReal Estate Management and Valuation
Housing deprivation is a multidimensional concept that can be measured using various indicators. This study focuses on severe housing deprivation and its components – overcrowding and housing conditions problems.
Dudek Hanna   +1 more
doaj   +1 more source

Remittances, Trade Liberalisation, and Poverty in Pakistan : The Role of Excluded Variables in Poverty Change Analysis [PDF]

open access: yes
This study attempts to assess the impact of two shocks - trade liberalisation and a decline in remittances from abroad- on poverty in Pakistan using a CGE framework.
A. R. Kemal, Rizwana Siddiqui
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

No. 18: The State of Food Insecurity in Blantyre City, Malawi [PDF]

open access: yes, 2013
Chronic food insecurity is considered to be one of the most important challenges facing the people and government of Malawi. Most attention tends to be given to the rural areas where the majority of the population live and where the prevalence of food ...
Chiweza, Asiyati, Mvula, Peter
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

EATING OUT: AN IMPORTANT SOURCE OF FOOD FOR THE POOR AND THE FOOD INSECURE [PDF]

open access: yes
Food consumption behaviors in food secure and food insecure households are compared. A two-stage budgeting and a double-hurdle model are used in the estimation. The results of the paper show that both food away from home and food at home are normal goods
Jensen, Helen H., Pan, Suwen
core   +1 more source

The Rise of Single Fathers: A Ninefold Increase Since 1960 [PDF]

open access: yes, 2013
A record 8% of households with minor children in the United States are headed by a single father, up from just over 1% in 1960, according to a Pew Research Center analysis of Decennial Census and American Community Survey data.The number of single father
Gretchen Livingston
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

THE IMPACT OF FINANCIAL AND ECONOMIC FACTORS ON HOUSEHOLD INCOME IN THE PRE-WAR AND WAR PERIODS

open access: yesФінансово-кредитна діяльність: проблеми теорії та практики
The article analyzes the state of household income and consumption in Ukraine in peacetime and wartime. The role of financial resources of the population in the financial system of the state is substantiated.
Myroslava Tymots   +4 more
doaj   +1 more source

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