Results 91 to 100 of about 319,510 (207)

A strong immune response in young adult honeybees masks their increased susceptibility to infection compared to older bees [PDF]

open access: yes, 2012
Honeybees, Apis mellifera, show age-related division of labor in which young adults perform maintenance ("housekeeping") tasks inside the colony before switching to outside foraging at approximately 23 days old. Disease resistance is an important feature
Baxter, Laura   +8 more
core   +4 more sources

Evaluation of diversity, specialization, and gene specificity in transcriptomes [PDF]

open access: yes, 2009
The transcriptome is a set of genes transcribed in a given tissue under specific conditions and can be characterized by a list of genes with their corresponding frequencies of transcription.
Humberto Reyes-Valdé   +1 more
core   +2 more sources

Genistein-induced mir-23b expression inhibits the growth of breast cancer cells [PDF]

open access: yes, 2015
Aim of the study: Genistein, an isoflavonoid, plays roles in the inhibition of protein tyrosine kinase phosphorylation, induction of apoptosis, and cell differentiation in breast cancer.
Avci, C.B.   +6 more
core   +2 more sources

Dysregulated homeostasis of acetylcholine levels in immune cells of RR-multiple sclerosis patients [PDF]

open access: yes, 2016
Multiple sclerosis (MS) is characterized by pro-inflammatory cytokine production. Acetylcholine (ACh) contributes to the modulation of central and peripheral inflammation.
Biagioni, Stefano   +11 more
core   +2 more sources

CONTRASTING EFFECTS OF AN MDM2 FUNCTIONAL POLYMORPHISM ON TUMOR PHENOTYPES [PDF]

open access: yes, 2017
Cancer predisposition by the cooperation of genetic variants, such as single nucleotide polymorphisms (SNPs), may be of much greater significance to public health than previously appreciated.
Ortiz, Guadalupe J, IV
core   +2 more sources

Exons, introns and DNA thermodynamics

open access: yes, 2005
The genes of eukaryotes are characterized by protein coding fragments, the exons, interrupted by introns, i.e. stretches of DNA which do not carry any useful information for the protein synthesis.
A. Stoltzfus   +11 more
core   +1 more source

Menadione-induced oxidative stress re-shapes the oxylipin profile of Aspergillus flavus and its lifestyle [PDF]

open access: yes, 2015
Aspergillus flavus is an efficient producer of mycotoxins, particularly aflatoxin B1, probably the most hepatocarcinogenic naturally-occurring compound.
Cigliano, Riccardo Aiese   +9 more
core   +2 more sources

One-step real-time duplex reverse transcription PCRs simultaneously quantify analyte and housekeeping gene mRNAs

open access: yesBioTechniques, 2004
We developed a one-step real-time duplex reverse transcription PCR (RT-PCR) method using the LightCycler® platform. This method allows simultaneous reverse transcription and real-time PCR amplification of two mRNAs of specific genes of interest (analyte ...
Chengming Wang   +3 more
doaj   +1 more source

Research Article [PDF]

open access: yes
Mixed modeling and sample size calculations for identifying housekeeping ...
Ary D   +5 more
core  

The bromodomain-containing protein Ibd1 links multiple chromatin related protein complexes to highly expressed genes in Tetrahymena thermophila

open access: yes, 2018
Background: The chromatin remodelers of the SWI/SNF family are critical transcriptional regulators. Recognition of lysine acetylation through a bromodomain (BRD) component is key to SWI/SNF function; in most eukaryotes, this function is attributed to ...
Burtch, Alyson   +9 more
core   +1 more source

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