Results 1 to 10 of about 174,210 (250)

Housekeeping and tissue-specific genes in mouse tissues [PDF]

BMC Genomics, 2007
Background This study aims to characterize the housekeeping and tissue-specific genes in 15 mouse tissues by using the serial analysis of gene expression (SAGE) strategy which indicates the relative level of expression for each transcript matched to the ...
St-Amand Jonny, Yoshioka Mayumi, Cadrin-Girard Jean F, Nishida Yuichiro, Kouadjo Kouame E   +4 more
doaj   +3 more sources

Further understanding human disease genes by comparing with housekeeping genes and other genes [PDF]

BMC Genomics, 2006
Background Several studies have compared various features of heritable disease genes with other so called non-disease genes, but they have yielded some conflicting results.
Chen Ting, Zhou Xianghong, Xu Min, Wang Li, Tu Zhidong, Sun Fengzhu   +5 more
doaj   +3 more sources

Housekeeping gene dysregulation in psoriasis: integrative multi‐cohort and single‐cell analysis reveals keratinocyte‐centric molecular mechanisms and diagnostic biomarkers

Frontiers in Immunology
BackgroundPsoriasis is a chronic immune-mediated skin disease driven by the interleukin-23/interleukin-17 cytokine axis, yet its immunopathogenesis remains incompletely understood.
Hao Tang, Jiacheng Wang, Shuhao Zhang, Guanglong Feng, Xiangshu Cheng, Xin Meng, Rui Chen, Jiaqi Wang, Yongshuai Jiang, Ruijie Zhang, Wenhua Lv   +10 more
doaj   +1 more source

The delayed effect of mustard gas on housekeeping gene expression in lung biopsy of chemical injuries

Biochemistry and Biophysics Reports, 2017
Objective: Sulfur mustard (SM) was used as a chemical weapon in Iraq-Iran war. Exposed people have major complications in important organs such as pulmonary system.
Marzieh Eghtedardoost, Zuhair Mohammad Hassan, Nayereh Askari, Alireza Sadeghipour, Mohammad Mahdi Naghizadeh, Sara Ghafarpour, Tooba Ghazanfari   +6 more
doaj   +1 more source

Identifying and validating housekeeping hybrid Prunus spp. genes for root gene-expression studies.

PLoS ONE, 2020
Prunus rootstock belonging to subgenera Amygdalus (peach), Prunus (plum) and Cerasus (cherry) are either from the same species as the scion or another one.
Adriana Bastias, Kristen Oviedo, Ruben Almada, Francisco Correa, Boris Sagredo   +4 more
doaj   +1 more source

Data highlighting miR-155 and GAPDH correlation

Data in Brief, 2019
This data represents the effect of miR-155 on the expression of commonly used housekeeping genes, GAPDH, Beta Actin, RPL13A, and U6. The human miR-155 and control RNA were transfected to A549 cells by electroporation.
Madhu Khanna, Sanjesh Saini, Malini Shariff, Larance Ronsard, Jitender K. Singh, Harish Kumar   +5 more
doaj   +1 more source

Feedforward regulation of Myc coordinates lineage-specific with housekeeping gene expression during B cell progenitor cell differentiation.

PLoS Biology, 2019
The differentiation of self-renewing progenitor cells requires not only the regulation of lineage- and developmental stage-specific genes but also the coordinated adaptation of housekeeping functions from a metabolically active, proliferative state ...
Isabel Ferreirós-Vidal, Thomas Carroll, Tianyi Zhang, Vincenzo Lagani, Ricardo N Ramirez, Elizabeth Ing-Simmons, Alicia G Gómez-Valadés, Lee Cooper, Ziwei Liang, Georgios Papoutsoglou, Gopuraja Dharmalingam, Ya Guo, Sonia Tarazona, Sunjay J Fernandes, Peri Noori, Gilad Silberberg, Amanda G Fisher, Ioannis Tsamardinos, Ali Mortazavi, Boris Lenhard, Ana Conesa, Jesper Tegner, Matthias Merkenschlager, David Gomez-Cabrero   +23 more
doaj   +1 more source

One-step real-time duplex reverse transcription PCRs simultaneously quantify analyte and housekeeping gene mRNAs

BioTechniques, 2004
We developed a one-step real-time duplex reverse transcription PCR (RT-PCR) method using the LightCycler® platform. This method allows simultaneous reverse transcription and real-time PCR amplification of two mRNAs of specific genes of interest (analyte ...
Chengming Wang, Dongya Gao, Alexander Vaglenov, Bernhard Kaltenboeck   +3 more
doaj   +1 more source

Housekeeping gene selection advisory: glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and β-actin are targets of miR-644a.

PLoS ONE, 2012
Results of overexpression or downregulation of a microRNA (miRNA) on its target mRNA expression are often validated by reverse-transcription and quantitative PCR analysis using an appropriate housekeeping gene as an internal control.
Kavleen Sikand, Jagjit Singh, Jey Sabith Ebron, Girish C Shukla   +3 more
doaj   +1 more source

Selection and Validation of Reference Candidate Genes for qRT-PCR Analysis in the Developing Fruit of Phyllanthus emblica L.

Horticulturae
Accurate normalization of target gene expression in qRT-PCR experiments requires the development of stable and efficient housekeeping reference genes, particularly for tissue-specific genes in a given organ.
Tianlei Pu, Jianmin Yuan, Wenlin Qu, Chengfei Liao, Xiao Lei, Kunjian Qian, Qiongling Zhao, Liangjia Shi, Lumin Zhang, Aizhong Liu   +9 more
doaj   +1 more source