Results 131 to 140 of about 174,210 (250)

What to Do if the qPCR Test for SARS-CoV-2 or Other Pathogen Lacks Endogenous Internal Control? A Simple Test on Housekeeping Genes. [PDF]

Biomedicines, 2023
Kuzan A, Tabakov I, Madej L, Mucha A, Fulawka L.   +4 more
europepmc   +1 more source

Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis

Advanced Science, EarlyView.
Our study identifies selenium deficiency as a hallmark of MASH pathogenesis. Dietary selenium supplementation enhances hepatic fatty acid oxidation (FAO) and attenuates MASH progression by activating the PPARα pathway via selenoprotein H (SELENOH). This selenium‐SELENOH‐PPARα nexus redefines the functional scope of selenoproteins, moving from redox ...
Yuwei Zhang, Yuchen Wang, Binbin Li, Xin Li, Chenyu Liu, Yanhao Chen, Cheng Tian, Dongmei Wang, Xiaosong Gu, Chunping Jiang, Yuda Wei, Qiurong Ding   +11 more
wiley   +1 more source

Multicondition expression profiling reveals limitations of canonical housekeeping genes. [PDF]

BMC Genomics
Projahn E, Walter M, Fuellen G, Möller S.   +3 more
europepmc   +1 more source

Identification of housekeeping genes of Candidatus Branchiomonas cysticola associated with epitheliocystis in Atlantic salmon (Salmo salar L.). [PDF]

Arch Microbiol, 2022
Mjølnerød EB, Srivastava A, Moore LJ, Plarre H, Nylund A.   +4 more
europepmc   +1 more source

DADA Enhances CD8+ T Cell Stemness to Improve Anti‐Tumor Immunity and Immunotherapy Efficacy

Advanced Science, EarlyView.
Diisopropylamine dichloroacetate (DADA) enhances CD8+ T cell stemness by improving OXPHOS and mitochondrial fitness in a PDK1‐depenpendent manner. This metabolic shift strengthens CD8+ T cell anti‐tumor immunity, improves responses to PD‐1 blockade, and endows CAR‐T cells with prolonged persistence and resistance to terminal exhaustion, highlighting a ...
Mingyue Bi, Fei Li, Heng Jiang, Lingling Gu, Mengjie Sun, Kunyu Lu, Pianpian Liu, Ruyue Xie, Wenqiang Ma, Meijuan Zheng, Xianwei Wang, Xuefu Wang, Jingjing Cong   +12 more
wiley   +1 more source

Correction: Stability and suitability of housekeeping genes in phlebotomine sand flies. [PDF]

Sci Rep
Sassù F, Vomáčková Kykalová B, Vieira CS, Volf P, Loza Telleria E.   +4 more
europepmc   +1 more source

Variable expression of eighteen common housekeeping genes in human non-cancerous kidney biopsies. [PDF]

PLoS One, 2021
Strauss P, Mikkelsen H, Furriol J.
europepmc   +1 more source

ZBTB21 Is a Dual Suppressor of Pyroptosis and MHC‐I Antigen Presentation That Promotes Tumor Immune Evasion

Advanced Science, EarlyView.
ZBTB21 is a transcription factor that epigenetically suppresses pyroptosis and MHC‐I antigen presentation, enabling tumor immune evasion. Genetic ablation of ZBTB21 activates pyroptotic cell death and enhances antigen presentation, recruiting CD8+ T cells to overcome immune checkpoint blockade resistance.
Lei Zhao, Linlin Sheng, Jianhao Qiu, Junjie Ma, Kai Jin, Binggong Zhao, Tianrun Miao, Jing Chen, Yehong Li, Zhan Zhang, Dongfeng Sun, Yongmeng Li, Hui Tian   +12 more
wiley   +1 more source

Normalization Challenges Across Adipocyte Differentiation and Lipid-Modulating Treatments: Identifying Reliable Housekeeping Genes. [PDF]

Int J Mol Sci
Ivanova Z, Petrova V, Penev T, Grigorova N.   +3 more
europepmc   +1 more source

Examining potential confounding factors in gene expression analysis of human saliva and identifying potential housekeeping genes. [PDF]

Sci Rep, 2022
Ostheim P, Alemu SW, Tichý A, Sirak I, Davidkova M, Stastna MM, Kultova G, Schuele S, Paunesku T, Woloschak G, Ghandhi SA, Amundson SA, Haimerl M, Stroszczynski C, Port M, Abend M.   +15 more
europepmc   +1 more source