Results 21 to 30 of about 174,210 (250)

Predicting housekeeping genes based on Fourier analysis. [PDF]

open access: yesPLoS ONE, 2011
Housekeeping genes (HKGs) generally have fundamental functions in basic biochemical processes in organisms, and usually have relatively steady expression levels across various tissues.
Bo Dong   +6 more
doaj   +4 more sources

Housekeeping genes in cancer: normalization of array data

open access: yesBioTechniques, 2005
Biological maintenance of cells under variable conditions should affect gene expression of only certain genes while leaving the rest unchanged. The latter, termed “housekeeping genes,” by definition must reflect no change in their expression levels ...
Anis H. Khimani   +9 more
doaj   +3 more sources

Assessment of common housekeeping genes as reference for gene expression studies using RT-qPCR in mouse choroid plexus [PDF]

open access: yesScientific Reports, 2021
Choroid plexus (ChP), a vascularized secretory epithelium located in all brain ventricles, plays critical roles in development, homeostasis and brain repair. Reverse transcription quantitative real-time PCR (RT-qPCR) is a popular and useful technique for
Kim Hoa Ho, Annarita Patrizi
doaj   +2 more sources

Mining housekeeping genes with a Naive Bayes classifier [PDF]

open access: yesBMC Genomics, 2006
Background Traditionally, housekeeping and tissue specific genes have been classified using direct assay of mRNA presence across different tissues, but these experiments are costly and the results not easy to compare and reproduce.
Aitken Stuart, De Ferrari Luna
doaj   +6 more sources

Regulatory architecture of cell identity genes and housekeeping genes. [PDF]

open access: yesTrends Cell Biol, 2023
Gene regulation and chromosome architecture are intimately linked. Genes with prominent roles in cell identity are often regulated by clusters of enhancer elements. By contrast, a recent study shows housekeeping genes are often regulated through clustering of promoters. We discuss here new regulatory insights for these two types of genes.
Dall'Agnese A, Young R.
europepmc   +3 more sources

Systematic Identification and Validation of Housekeeping and Tissue-Specific Genes in Allotetraploid Chenopodium quinoa

open access: yesHorticulturae, 2021
Quinoa is a gluten-free food crop that contains all the essential amino acids and vitamins. The selection of proper housekeeping and tissue-specific genes is the crucial prerequisite for gene expression analysis using the common approach, real-time ...
Bing He   +6 more
doaj   +1 more source

Evaluation and validation of housekeeping genes as reference for gene expression studies in pigeonpea (Cajanus cajan) under drought stress conditions. [PDF]

open access: yesPLoS ONE, 2015
Gene expression analysis using quantitative real-time PCR (qRT-PCR) is a very sensitive technique and its sensitivity depends on the stable performance of reference gene(s) used in the study.
Pallavi Sinha   +5 more
doaj   +1 more source

Housekeeping genes in prostate tumorigenesis [PDF]

open access: yesInternational Journal of Cancer, 2009
AbstractHousekeeping (HK) genes are involved in basic cellular functions and tend to be constitutively expressed across various tissues and conditions. A number of studies have analyzed the value of HK genes as an internal standard for assessing gene expression, but the role of HK genes in cancer development has never been specifically addressed.
Jinyoung, Byun   +2 more
openaire   +2 more sources

Human housekeeping genes are compact [PDF]

open access: yesTrends in Genetics, 2003
We identify a set of 575 human genes that are expressed in all conditions tested in a publicly available database of microarray results. Based on this common occurrence, the set is expected to be rich in "housekeeping" genes, showing constitutive expression in all tissues.
Eisenberg, Eli, Levanon, Erez Y.
openaire   +3 more sources

Housekeeping gene stability in Pesudomonas aeruginosa PAO1 under the pressure of commonly used antibiotics in molecular microbiology assays

open access: yesFrontiers in Microbiology, 2023
Pseudomonas aeruginosa is an opportunistic human pathogen notorious for its remarkable capacity of multi-drug resistance, and has become one of the most important model bacteria in clinical bacteriology research.
Lingning Meng   +8 more
doaj   +1 more source

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