Results 71 to 80 of about 156,333 (265)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Relationship between CO2 Concentration and Environmental Parameters with Sick Building Syndrome in School and House Settings in Babol, Iran

open access: yesJournal of Mazandaran University of Medical Sciences, 2019
Background and purpose: Lack of healthy air in classrooms and homes will reduce the level of health and disrupts students’ learning. The aim of this study was to determine the relationship between CO2 concentration and other environmental parameters with
Zahra Aghalari   +5 more
doaj  

The role of Linear Pottery houses in the process of neolithisation

open access: yesDocumenta Praehistorica, 2013
A Linear Pottery settlement represents on a certain scale a symbiosis of different soci-economic groups of inhabitants in one given space. The role and status of artefacts can be de- scribed according to individual types of houses.
Ivan Pavlu
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

House-related practices as markers of the Neolithic expansion from Anatolia to the Balkans

open access: yesБългарско е-Списание за Археология, 2014
Following the assumption that the Neolithic witnessed the first widespread appearance of permanent houses and households, in line with the adoption of sedentism, this article examines the relevance of residential and construction practices to our ...
Maxime N. Brami
doaj  

Houses and Daily Life in Islamic Portugal (12th–13th Century): Mértola in the Context of Gharb

open access: yesArts, 2018
This is an overview of the houses in southern Portugal, at the final stages of the Islamic period, using Mértola as the case study. Recent archaeological works, performed in different places, give us information on the houses’ organization, as
Santiago Macias
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Investigation of Comfort Temperature and Occupant Behavior in Japanese Houses during the Hot and Humid Season

open access: yesBuildings, 2014
In order to clarify the comfort temperature and to investigate the behavioral adaptation in Japanese houses, we have conducted a thermal comfort survey and occupant behavior survey in 30 living rooms during the hot and humid season in the Kanto region of
Hom B. Rijal
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

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