Results 71 to 80 of about 156,646 (264)
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
House-related practices as markers of the Neolithic expansion from Anatolia to the Balkans
Българско е-Списание за Археология, 2014 Following the assumption that the Neolithic witnessed the first widespread appearance of permanent houses and households, in line with the adoption of sedentism, this article examines the relevance of residential and construction practices to our ...
Maxime N. Brami
doaj
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
The role of Linear Pottery houses in the process of neolithisation
Documenta Praehistorica, 2013 A Linear Pottery settlement represents on a certain scale a symbiosis of different soci-economic groups of inhabitants in one given space. The role and status of artefacts can be de- scribed according to individual types of houses.
Ivan Pavlu
doaj +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Psychiatry and Clinical Psychopharmacology, 2017 Objective: The objective of this study is to develop a risk-screening questionnaire appropriate for cultural characteristics in detection of alcohol- and drug-use level through utilization of Addiction Profile Index (API) and perform the reliability and ...
Kültegin Ögel +2 more
doaj +1 more source
Houses and Daily Life in Islamic Portugal (12th–13th Century): Mértola in the Context of Gharb
Arts, 2018 This is an overview of the houses in southern Portugal, at the final stages of the Islamic period, using Mértola as the case study. Recent archaeological works, performed in different places, give us information on the houses’ organization, as
Santiago Macias
doaj +1 more source
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Buildings, 2014 In order to clarify the comfort temperature and to investigate the behavioral adaptation in Japanese houses, we have conducted a thermal comfort survey and occupant behavior survey in 30 living rooms during the hot and humid season in the Kanto region of
Hom B. Rijal
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source