Results 71 to 80 of about 2,575,445 (348)

Houses of Experiment: Modern Housing and the Will to Laboratorization [PDF]

open access: yesInternational Journal of Urban and Regional Research, 2013
AbstractThis article adds historical and geographical specificity to the link between city building and laboratorization processes. It does so by way of the example of housing in mid‐twentieth‐centuryBritain. Housing provision at this time saw an intensification of the relationship between architectural design and science by way of the emergent field ...
Jacobs, Jane, Strebel, Ignaz
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Dr. Milan Glavinić, architect (Belgrade 1891 - Belgrade 1968): Addenda to the biography [PDF]

open access: yesNasleđe, 2016
The paper supplies further data for a biography of Milan Glavinić, such as information on his participation in the Balkan Wars and the First World War and his broad social and political activity.
Latinčić Olga
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Hannes Zebedin: Living in Glass Houses [PDF]

open access: yes, 2009
Catalogue essay for Hannes Zebedin exhibition at Secession, Vienna.
Hammonds, Kit
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

From the surface to the seafloor: How giant larvaceans transport microplastics into the deep sea. [PDF]

open access: yes, 2017
Plastic waste is a pervasive feature of marine environments, yet little is empirically known about the biological and physical processes that transport plastics through marine ecosystems.
Choy, C Anela   +4 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Of Hearths and Houses [PDF]

open access: yes, 1996
During the 1993 East Texas Archeological Field School conducted at the Tyson site (41SY92) in western Shelby County, the junior author had an opportunity to participate in the excavation of a Caddoan hearth.
Middlebrook, Ryan, Middlebrook, Tom
core   +1 more source

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