Results 101 to 110 of about 3,653,103 (356)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Providing ramps during lay has larger impacts on laying hens than ramps at rearing

Poultry Science
: Commercial laying hen housing is shifting from traditional cages to non-cage housing systems, such as the aviary, which has gained popularity due to potential for more species-typical behavior.
M.J. Toscano, A.S. Jalali, J.M. Siegford, A. Stratmann   +3 more
doaj   +1 more source

Protocol voor meting van lachgasemissie uit huisvestingssystemen in de veehouderij 2010 = Measurement protocol for nitrous oxide emission from housing systems in livestock production 2010 [PDF]

, 2011
This report describes a measurement protocol for nitrous oxide emissions from animal housing systems. The protocol is based on sampling periods of 24 hours spread over one year and can be applied in specified animal ...
Groenestein, C.M., Mosquera Losada, J., Ogink, N.W.M.   +2 more
core  

Animal welfare in poultry production systems: impact of EU standards on world trade [PDF]

, 2008
Animal welfare receives more legislative attention in the European Union (EU) than in many other regions of the world. Animal welfare standards for poultry are generally taken to be higher in the EU than in producing countries exporting to the EU ...
Achterbosch, T.J., Horne, P.L.M., van
core   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Influence of light exposure during late incubation, early feeding, and litter access posthatch on the stress response and body weight gain in laying hen chicks

Journal of Applied Poultry Research
SUMMARY: In-ovo sexing opens the door to on-farm hatching in the laying hen sector, but knowledge on the implications of different hatching system factors remains limited.
Catharina M.H. Broekmeulen, Yamenah Gómez, Sabine G. Gebhardt-Henrich, Bettina Almasi, Rupert M. Bruckmaier, Michael J. Toscano   +5 more
doaj   +1 more source

Statistical tools to improve assessing agreement between several observers

Animal, 2014
In the context of assessing the impact of management and environmental factors on animal health, behaviour or performance it has become increasingly important to conduct (epidemiological) studies in the field.
I. Ruddat, B. Scholz, S. Bergmann, A.-L. Buehring, S. Fischer, A. Manton, D. Prengel, E. Rauch, S. Steiner, S. Wiedmann, L. Kreienbrock, A. Campe   +11 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Reliability of Palpation using three-dimensional keel bone models

Journal of Applied Poultry Research
Summary: Keel bone damage (KBD), including both deviations and fractures, is an important and wide-spread animal welfare problem of laying hens especially in non-cage housing systems.
E. Çavuşoğlu, M.J. Toscano, S.G. Gebhardt-Henrich   +2 more
doaj   +1 more source

Protocol voor meting van methaanemissie uit huisvestingssystemen in de veehouderij 2010 = Measurement protocol for methane emission from housing systems in livestock production 2010 [PDF]

, 2011
This report describes a measurement protocol for methane emissions from animal housing systems. The protocol is based on sampling periods of 24 hours spread over one year and can be applied in specified animal ...
Groenestein, C.M., Mosquera Losada, J., Ogink, N.W.M.   +2 more
core   +1 more source