Results 71 to 80 of about 3,653,103 (356)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Early Onset of Laying and Bumblefoot Favor Keel Bone Fractures
Animals, 2015 Numerous studies have demonstrated influences of hybrid, feed, and housing on prevalence of keel bone fractures, but influences of behavior and production on an individual level are less known.
Sabine G. Gebhardt-Henrich +1 more
doaj +1 more source
Comparison of animal welfare on conventional and organic dairy farms [PDF]
, 2000 Introduction: During the last years, concern has increased concerning animal welfare at the farm level. The Associations of Organic Agriculture have elaborated minimum requirements regarding animal welfare.
Hörning, Bernhard
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Veterinární Medicína, 2007 Epidemiological studies comparing risk factors for subclinical mastitis (SM) in organic (OP) and conventional dairy production systems (CP) are lacking. In 60 OP and 60 CP farms, 970 cows were used to study risk factors for SM at 31 days postpartum. Cows
M.G. Doherr +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Les Cahiers de la Recherche Architecturale, Urbaine et Paysagère, 2022 This article attempts to restore a reflection resulting from an empirical observation of animal space in rural houses in Algeria, by considering the processes involved in their vernacular consolidation and those involved in their contemporary ...
Latifa Khettabi
doaj +1 more source
To Group or Not to Group? Good Practice for Housing Male Laboratory Mice
Animals, 2017 Simple Summary Wild mice live in territories inhabited by one adult male, several females, and their offspring. This cannot be replicated in the laboratory, so male mice are usually housed in single-sex groups or individually.
Sarah Kappel, P. Hawkins, M. Mendl
semanticscholar +1 more source
New ways of regulating organic food and farming in Europe [PDF]
, 2010 There is a paradigm shift needed in standard setting towards assessing progress rather than failure. Such systems needs good subject-related principles and objectives (e.g. for good animal housing).
Schmid, Otto
core
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source