Results 31 to 40 of about 103,955 (275)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Housing in Slovakia: COVID-19 pandemics impacts on regions, affordability and residential development

Regional Studies, Regional Science
Housing affordability has become a critical challenge in Europe, particularly in post-socialist contexts with ownership-oriented tenure systems and weak rental sectors. Housing affordability in Slovakia ranks among the least affordable housing markets in
Ján Výbošťok, Dušan Paur
doaj   +1 more source

Assessing the subjective perception of urban households on the criteria representing sustainable housing affordability

Scientific African, 2021
Housing affordability is typically assessed in economic terms, but housing affordability concerns transcend mere housing cost and its relationship to income, to wider issues of social wellbeing and sustainability.
Ikenna Stephen Ezennia, Sebnem Onal Hoskara   +1 more
doaj   +1 more source

The Housing Affordability Gap for Extremely Low-Income Renters in 2013 [PDF]

, 2015
This brief provides information on national trends in housing affordability for ELI renter households, as well as insights into which major counties are making the most and least progress on closing the housing affordability gap.
Josh Leopold, Katya Abazajian, Liza Getsinger, Pamela Blumenthal, Reed Jordan   +4 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

The Greater Boston Housing Report Card 2003: An Assessment of Progress on Housing in the Greater Boston Area [PDF]

, 2004
Presents an annual survey of the state of housing in Greater Boston: market conditions; housing production; rents, home prices, and affordability; and public spending and support.
Barry Bluestone, Bonnie Heudorfer
core   +4 more sources

Affordable Housing

Affordable ...
  +6 more sources

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Exploring Affordability in the Irish Housing Market. ESRI WP593, June 2018 [PDF]

, 2018
This paper examines housing affordability in Ireland by looking at the distribution of housing costs across households. Using microdata from the SILC survey over the period 2005-2015, the contribution of this paper is threefold.
Corrigan, Eoin, Foley, Daniel, McQuinn, Kieran, O’Toole, Conor, Slaymaker, Rachel   +4 more
core  

Identifying High‐Impact Solutions to Address Racial and Ethnic Health Disparities in Lupus: A Consensus‐Based Approach

Arthritis Care &Research, EarlyView.
Objective We conducted formative research aimed at identifying solutions that address inequitable health outcomes in lupus due to adverse social determinants of health (SDoH). Methods We conducted a search for keywords, which provided insights into potential solutions and initiatives underway. An advisory panel of lupus experts iteratively reviewed the
Joy Buie, Michael P. Fisher, Kristen Backor, Hannah Tyldsley, Ashira Blazer, Candace Feldman, Andrea Knight, S. Sam Lim, Barbara Ann Polk, Ed Yelin, Edith Williams, Karen H. Costenbader   +11 more
wiley   +1 more source