Results 91 to 100 of about 817,941 (312)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Assessing the impact of economic variables on Romania's real estate market evolution: risk, uncertainty, and investment dynamics

open access: yesTechnological and Economic Development of Economy
This study examines Romania’s real estate market (2003–2023), analyzing economic variables’ impact on housing demand and investment trends through PLS-SEM and regression analysis.
Mioara Chirita   +6 more
doaj   +1 more source

Differentiation of Real Estate Market in Istanbul between 1995, 2005 [PDF]

open access: yes
Due to migration and rapidly increasing urban population settlement in urban land, lacking any planning or infrastructure, in addition to the destruction of the 17th August 1999 earthquake, it is necessary to examine uncertainty of housing demand and ...
Funda Yirmibesoglu
core  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Housing Demand with Random Group Effects [PDF]

open access: yes
This paper examines the random group effect, which has usually not been considered in traditional housing demand studies. Frequently, group level variables are used in housing demand estimation due to the data constraint.
Sue-Jing Lin, Wen-chieh Wu
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Spanish housing markets during the first phase of the rural-urban transition process [PDF]

open access: yes
This paper discusses how Spain’s housing markets reacted to the far-reaching changes that affected the demand for dwellings during the first phase of the rural-urban transition process. To this end, we construct a new hedonic index of real housing prices
Joan R. Roses   +2 more
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

How healthy and sustainable is the Dutch housing mix? Measuring and comparing the theoretical housing market balance of Dutch regional housing markets

open access: yesUrban, Planning and Transport Research, 2015
Housing and its distribution over groups of households dominates debates on urban socio-spatial justice. Amsterdam even received the label ‘Just City’ as the large stock of social housing in the core of the city is said to increase societal equity ...
Leonie B. Janssen-Jansen   +1 more
doaj   +1 more source

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