Results 1 to 10 of about 172,874 (194)
Frontiers in ImmunologyIntroductionR21, the most efficacious malaria vaccine to date, has been recommended by the World Health Organization (WHO) for the prevention of malaria in children. The current vaccination schedule requires three intramuscular doses per year. Optimizing
Ekta Mukhopadhyay +3 more
doaj +1 more source
Med Research, EarlyView.This study examined the relative contributions of modifiable risk factors to cardiovascular diseases in adults with hypertension. More favorable risk factor profiles were consistently associated with lower risks across all outcomes. Beyond blood pressure, nicotine exposure showed comparatively larger population attributable fractions.
Shengtao Wei +10 more
wiley +1 more source
Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood +7 more
wiley +1 more source
Real Estate Management and ValuationHousing demand for newly constructed housing in Poland has observed some changes along the recent economic perturbations that were related to the Covid-19 pandemic and the Russian war on Ukraine, but despite significant changes in the mortgage interest ...
Łaszek Jacek, Olszewski Krzysztof
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Depopulation of Cities and Housing Decisions of University Graduates
Real Estate Management and Valuation, 2019 Predicting the population size of a city is one of the key tasks preceding the creation of city development plans, seeing as how urban space management should be adequate to current and forecasted economic and social trends, including demographic ones ...
Źróbek-Różańska Alina
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Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Malaria JournalBackground Malaria remains a major public health burden in Africa, particularly among children under five years of age. By consolidating findings across randomized controlled trials on the RTS,S and R21 malaria vaccines, this study seeks to provide an ...
Khulud Mahmood Nurani +9 more
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Revisiting Inductively Coupled Wireless Coils in MRI: Mitigating Over‐Coupling With Preamplifiers
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose Inductively coupled coils enhance local MRI sensitivity, yet strong coupling with nearby primary coils typically causes resonance splitting and impedance mismatch, which are traditionally considered detrimental. This work investigates why inductively coupled coils can still function effectively even in the presence of severe coupling ...
Ming Lu, John C. Gore, Xinqiang Yan
wiley +1 more source
TrialsIntroduction Progress in malaria control has stalled since 2015, highlighting the need for new control tools. The R21/Matrix-M (R21) malaria vaccine, a pre-erythrocytic vaccine recently approved by WHO for small children, may be one of these tools.
Edgard D. Dabira +12 more
doaj +1 more source