Results 91 to 100 of about 186,828 (260)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

How Do Housing Quality and Environmental Pollution Affect Older Adults’ Self-Rated Health? The Mediating Effect of Depression and Social Capital

Buildings
With accelerated population aging, the importance of older adults’ self-rated health is constantly increasing. Self-rated health is influenced by complex relationships between the built environment and psychosocial factors.
Jinhui Song, Wen Zuo, Xuefang Zhuang, Rong Wu   +3 more
doaj   +1 more source

Housing quality and its impact on Acute Respiratory Infection (ARI) symptoms among children in Punjab, Pakistan. [PDF]

PLOS Glob Public Health, 2022
Aftab A, Noor A, Aslam M.
europepmc   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Evaluation the Influences of housing quality in rural settlements vitality Khavmyrabad district, Mariwan township [PDF]

تحقیقات کاربردی علوم جغرافیایی, 2016
Research goall is survey in the situation of quality of housing and rural vitality and survey of relationship of housing quality and vitality of rural settlements.
Behrooz Mohammadi yeganeh, Mehdi cheraghi, fovad samadi   +2 more
doaj  

Effect of Housing Quality on the Mental Health of University Students during the COVID-19 Lockdown. [PDF]

Int J Environ Res Public Health, 2022
Morganti A, Brambilla A, Aguglia A, Amerio A, Miletto N, Parodi N, Porcelli C, Odone A, Costanza A, Signorelli C, Serafini G, Amore M, Capolongo S.   +12 more
europepmc   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

Low housing quality, unmet social needs, stress and depression among low-income smokers. [PDF]

Prev Med Rep, 2022
Garg R, McQueen A, Wolff JM, Skinner KE, Kegler MC, Kreuter MW.   +5 more
europepmc   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

Housing Quality in a Rural and an Urban Settlement in South Africa. [PDF]

Int J Environ Res Public Health, 2021
Mathee A, Moyes J, Mkhencele T, Kleynhans J, Language B, Piketh S, Moroe E, Wafawanaka F, Martinson N, McMorrow M, Tempia S, Kahn K, Cohen C.   +12 more
europepmc   +1 more source