Results 71 to 80 of about 934,795 (307)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Risk Shocks and Housing Markets [PDF]
This paper analyzes the role of uncertainty in a multi-sector housing model with financial frictions. We include time varying uncertainty (i.e. risk shocks) in the technology shocks that affect housing production.
Dorofeenko, Victor +2 more
core +3 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Tilted platforms: rental housing technology and the rise of urban big data oligopolies. [PDF]
Urban Transform, 2021 Boeing G +3 more
europepmc +1 more source
A Filtering Model with Steady-State Housing [PDF]
This paper presents a filtering model of the housing market which is similar to Sweeney's (1974b), except that the maintenance technology is such that housing can be maintained at a constant quality level as well as downgraded, and population at each ...
Ralph Braid, Richard Arnott
core
Draw like a builder, build like a writer. And the crack is in the detail [PDF]
, 2007 As the inevitable building by numbers ensues, London’s Thames Gateway becomes one of many playgrounds for bar charting enthusiasts. Houses measured by the thousands and little clues as to where it is, that ghost in the machine, what they are, the ...
Frith, Edmund, Graef, Alexander
core
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Advancing Sustainable 3D-Printed Concrete: A Bibliometric Study on Financing Housing Options [PDF]
MATEC Web of ConferencesThe emergence of 3D-printed concrete technology presents promising opportunities for sustainable housing solutions. However, the limited knowledge of financing mechanisms poses a considerable barrier to these projects' widespread implementation and ...
Kubjana Lucy +2 more
doaj +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Universal housing technologies
, 2018 Through its unit Integrated Technologies for Quality of Living [L1], CNR-ISTI is a partner of a soon-to-commence project, UNIversalhoUSING. Its purpose is to establish a set of design guidelines for near-zero-emission buildings strictly integrated with their technological facilities, to ensure full compliance with both the existing norms and to meet ...
Salerno E, Fusco G
openaire +2 more sources