Results 91 to 100 of about 44,575 (191)

License to Replicate: Mechanisms of Licensing Eukaryotic Origins for DNA Replication

open access: yesBioEssays, Volume 48, Issue 1, January 2026.
Origin licensing constitutes the first step in initiating eukaryotic genome replication. Licensed origins are marked by an MCM double hexamer complex. This article reviews the molecular mechanisms of MCM double hexamer loading in yeast and higher eukaryotes, based on insights gained from biochemical reconstitution and structural analyses.
Victoria Frisbie, Franziska Bleichert
wiley   +1 more source

Polysaccharides of St. John’s Wort Herb Stimulate NHDF Proliferation and NEHK Differentiation via Influence on Extracellular Structures and Signal Pathways

open access: yesAdvances in Pharmacological Sciences, 2012
St. John's Wort herb extracts often contain undesirable or volitional polysaccharides. As polysaccharides exhibit structure-dependent biological functions in the present study water-soluble polysaccharides were extracted from herb material, fractionated ...
S. Abakuks, A. M. Deters
doaj   +1 more source

Targeting the TRIM28–EZH2 Protein–Protein Interface With Cysteine‐Reactive Covalent Inhibitors: A Computational Blueprint for Cancer Therapy

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
Graphical overview of the computational strategy employed to disrupt the oncogenic TRIM28EZH2 proteinprotein interaction. The workflow illustrates proteinprotein docking to define the interaction interface, cysteine‐focused covalent virtual screening targeting EZH2 Cys144, covalent docking, molecular dynamics simulations, and MM‐GBSA binding free ...
Ibrahim Oluwatobi Kehinde   +4 more
wiley   +1 more source

The distribution of haptoglobin types in various regions of Turkey

open access: yesThe Turkish Journal of Pediatrics, 1993
The distribution of haptoglobin (Hp) types and the gene frequencies of Hp1 in various regions' of Turkey are discussed. The Hp1 gene frequency ranged between 20.4 percent for Turks living in the eastern part of Turkey and 32.6 percent in those who
M Aksoy, S Erdem
doaj  

Seed germination traits reveal naturalization potential: Global insights from temperate European herbaceous species

open access: yesJournal of Ecology, Volume 114, Issue 1, January 2026.
This study provides global‐scale evidence that the naturalization of European herbaceous species is related to specific germination traits acquired in the native range. The findings indicate that traits such as high germinability, low stratification requirements and responsiveness to scarification act as preadaptations that facilitate naturalization by
Margherita Gioria   +14 more
wiley   +1 more source

THE DISTRIBUTIONOF HAPTOGLOBIN TYPE IN BANDARABAS (S. OF IRAN)

open access: yesIranian Journal of Public Health, 1978
The distribution of haptoglobin types of Iranian living in Bandaranbas (n=1246) is reported. Hp1 gene frequencies reported in the literature for different populations in Iran are given.
D.D.Farhud   +2 more
doaj  

Concepts of quantum non-Markovianity: a hierarchy

open access: yes, 2018
Markovian approximation is a widely-employed idea in descriptions of the dynamics of open quantum systems (OQSs). Although it is usually claimed to be a concept inspired by classical Markovianity, the term quantum Markovianity is used inconsistently and ...
Hall, Michael J. W.   +2 more
core   +1 more source

Epigenetic memory is governed by an effector recruitment specificity toggle in Heterochromatin Protein 1

open access: yesNature Communications
HP1 proteins are essential for establishing and maintaining transcriptionally silent heterochromatin. They dimerize, forming a binding interface to recruit diverse chromatin-associated factors.
Amanda Ames   +8 more
doaj   +1 more source

Características fisiológicas de microtomateiros fitocromo-mutantes Physiological characteristics of micro-tomato (Lycopersicon esculentum P. Miller) phytochrome-mutants

open access: yesCiência e Agrotecnologia, 2009
Objetivou-se, neste trabalho, caracterizar aspectos fisiológicos de microtomateiros (Lycopersicon esculentum P. Miller cv. Micro-Tom) fitocromo-mutantes.
Hyrandir Cabral de Melo   +4 more
doaj   +1 more source

A perturbative approach for the dynamics of the quantum Zeno subspaces

open access: yes, 2004
In this paper we investigate the dynamics of the quantum Zeno subspaces which are the eigenspaces of the interaction Hamiltonian, belonging to different eigenvalues.
A. Messiah   +8 more
core   +1 more source

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