Results 171 to 180 of about 44,575 (191)

Chromosomal Distribution of Heterochromatin Protein 1 (HP1) in Drosophila: a Cytological Map of Euchromatic HP1 Binding Sites

Genetica, 2003
The Heterochromatin Protein 1 (HP1) is a conserved protein which is best known for its strong association with the heterochromatin of Drosophila melanogaster. We previously demonstrated that another important property of HP1 is its localization to the telomeres of Drosophila, a feature that reflects its critical function as a telomere capping protein ...
FANTI, Laura, BERLOCO M., PIACENTINI, Lucia, PIMPINELLI, Sergio   +3 more
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Enforcing silencing: dynamic HP1 complexes in Neurospora

Nature Structural & Molecular Biology, 2012
Analysis of the Neurospora crassa chromodomain protein CDP-2, a component of a newly characterized HP1-containing complex, reveals a second gene-silencing mechanism and provides insights into the dynamic nature of chromatin domains that possess shared components.
Lori L, Wallrath, Sarah C R, Elgin
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HP1 Complexes and Heterochromatin Assembly

2003
Since its discovery almost two decades ago, heterochromatin protein 1 (HP1) has emerged as a major player in the transcriptional regulation of both heterochromatic and euchromatic genes as well as the mechanics of chromosome segregation and the functional and structural organization of the interphase nucleus.
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HP1 and the dynamics of heterochromatin maintenance

Nature Reviews Molecular Cell Biology, 2004
Heterochromatin maintenance is crucial for the clonal inheritance of cell identity, to ensure the proper segregation of chromosomes and the regulation of gene expression. Although it is architecturally stable, heterochromatin has to be flexible to cope with disrupting events such as replication.
Christèle, Maison, Geneviève, Almouzni
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Functions of HP1 in preventing chromosomal instability

Cell Biochemistry and Function
AbstractChromosomal instability (CIN), caused by errors in the segregation of chromosomes during mitosis, is a hallmark of many types of cancer. The fidelity of chromosome segregation is governed by a sophisticated cellular signaling network, one crucial orchestrator of which is Heterochromatin protein 1 (HP1).
Zexian Ding, Lei Peng, Jinghua Zeng, Kejia Yuan, Yan Tang, Qi Yi   +5 more
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Conserved properties of HP1(Hsalpha).

Gene, 2004
Heterochromatin protein 1 Hsalpha (HP1(Hsalpha)) is one of three human proteins that share sequence similarity with Drosophila HP1. HP1 proteins are enriched at centric heterochromatin and play a role in chromatin packaging and gene regulation. In humans, HP1(Hsalpha) is down-regulated in highly invasive/metastatic breast cancer cells, compared to ...
Laura E, Norwood, Stephanie K, Grade, Diane E, Cryderman, Karrie A, Hines, Nicholas, Furiasse, Rafael, Toro, Yuhong, Li, Archana, Dhasarathy, Michael P, Kladde, Mary J C, Hendrix, Dawn A, Kirschmann, Lori L, Wallrath   +11 more
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HP1 proteins—What is the essential interaction?

Russian Journal of Genetics, 2010
There are three mammalian HP1 genes, Cbx5 (encoding HP1alpha), Cbx1 (encoding HP1beta) and Cbx3 (encoding HP1gamma). Despite their high degree of sequence homology mutational analysis has revealed different phenotypes indicating that they possess different functions. Notably, the Cbx1 mutation is lethal in its homozygous condition.
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HP1 shapes embryonic genome architecture

Nature Structural & Molecular Biology, 2021
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CdTe hp1

2010
P. Villars, K. Cenzual, J. Daams, R. Gladyshevskii, O. Shcherban, V. Dubenskyy, V. Kuprysyuk, I. Savysyuk   +7 more
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ReO3 hp1

2012
P. Villars, K. Cenzual, R. Gladyshevskii, O. Shcherban, V. Dubenskyy, V. Kuprysyuk, I. Savysyuk, R. Zaremba   +7 more
openaire   +1 more source