A new model for the HPA axis explains dysregulation of stress hormones on the timescale of weeks
Stress activates a complex network of hormones known as the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is dysregulated in chronic stress and psychiatric disorders, but the origin of this dysregulation is unclear and cannot be explained by ...
Omer Karin +6 more
semanticscholar +1 more source
Background Early life exposure to adverse environments, and maternal stress in particular, has been shown to increase risk for metabolic diseases and neurobehavioral disorders. While many studies have examined the hypothalamic-pituitary-adrenal axis (HPA
Johanna R. Jahnke +3 more
semanticscholar +1 more source
Effects of intrauterine exposure to synthetic glucocorticoids on fetal, newborn, and infant hypothalamic-pituitary-adrenal axis function in humans : a systematic review [PDF]
BACKGROUND: Synthetic glucocorticoids are commonly used in reproductive medicine. Fetal organ systems are highly sensitive to changes in the intrauterine environment, including overexposure to glucocorticoids.
1994 Effect of corticosteroids for fetal maturation on perinatal outcomes +257 more
core +2 more sources
Neonatal Intracranial Hemorrhage with a Dramatic Outcome Due to Maternal Anti CD36 Antibodies
Fetal/neonatal allo-immune thrombocytopenia (FNAIT) results from maternal immunization against fetal platelet-specific antigens (HPA) inherited from the father. Most cases involve HPA located on glycoproteins (GP) IbIX, IaIIa and IIbIIIa.
Gérald Bertrand +5 more
doaj +1 more source
Cognitive, Emotional, Behavioral and Physiological Evaluation of the Relationship Between Brain and Gut Microbiota [PDF]
The aim of this study is to examine the effect of gut microbiota on brain functions, mood and psychiatric disorders such as depression, anxiety and behavioral addictions, neurotransmitter levels, cognitive processes such as self-control, decision making ...
Selim Günüç, Aylin Şendemir
doaj
The Involvement of Hypothalamus–Pituitary–Adrenal (HPA) Axis in Suicide Risk
Stress and Hypothalamic–Pituitary–Adrenal (HPA) axis dysregulation play a major role in various pathophysiological processes associated with both mood disorders and suicidal behavior.
I. Berardelli +5 more
semanticscholar +1 more source
Leptin fails to blunt the lipopolysaccharide-induced activation of the hypothalamic-pituitary-adrenal axis in rats [PDF]
Copyright @ 2013 The authors. This work is licensed under a Creative Commons Attribution 3.0 Unported License.Obesity is a risk factor for sepsis morbidity and mortality, whereas the hypothalamic-pituitary-adrenal (HPA) axis plays a protective role in ...
Ahima +40 more
core +1 more source
Foetal and neonatal alloimune thrombocytopenia as a rare exapmle of thrombocytopenia in newborn
Foetal and neonatal alloimmune thrombocytopenia (FNAIT) is caused by antigenic incompatibility of platelets between a pregnant woman and her child, resulting in producing antibodies by a mother against specific antigens (HPA- Human Platelet Antigens ...
Maciej Kamiński +6 more
doaj +1 more source
Objectives This paper reports on the trend of the stressogenic stimulus caused by a repeated exposure to 1-methylnaphthalene (1-MN) vapors at the nominal concentrations of 0 mg/m 3 (the control restrainer), 50 mg/m 3 or 200 mg/m 3 in the nose-only ...
Radosław Świercz, Maciej Stępnik
doaj +1 more source
The photochemistry of carbon monoxide in the stratosphere and mesosphere evaluated from observations by the Microwave Limb Sounder on the Aura satellite [PDF]
The photochemical production and loss rates for carbon monoxide (CO) in the stratosphere and mesosphere are evaluated using measurements from the Aura Microwave Limb Sounder (MLS) and the Atmospheric Chemistry Experiment-Fourier Transform Spectrometer ...
A. Lambert +55 more
core +2 more sources

