Results 91 to 100 of about 185,243 (332)

两种血清苯丙氨酸高效液相色谱测定法的比较

open access: yesZhongguo shiyan zhenduanxue, 2005
目的对两种血清苯丙氨酸高效液相色谱测定法进行比较。方法对高效液相色谱-紫外检测法(HPLC-UV)和高效液相色谱-荧光检测法(HPLC-FLD),从线性范围,检测限,精密度等参数上进行比较,用两种方法分别测定了正常儿童和一组PKU患儿血清phe值,对结果进行统计分析。结果HPLC-UV法和HPLC-FLD法的线性范围分别为61512μmol/L和121220μmol/L,最低检测限分别为0.75μmol/L和3μmol/L,平均回收率分别为98.6%和102.5 ...
唐爱国, 洪敏, 莫喜明, 陈若虹
doaj  

Ultrasound‐Triggered Nanobubbles for Endothelial‐Targeted Drug Delivery in the Detection and Treatment of Doxorubicin‐Induced Cardiotoxicity

open access: yesAdvanced Healthcare Materials, EarlyView.
The DA/VTP‐NBs selectively recognized cardiac ECs damaged by DIC and achieved cell‐level targeted imaging. Then US‐triggered controlled release successfully enabled the release of DAPA within the DA/VTP‐NBs at the site of injury. This precise on‐demand drug release approach amplifies a series of localized therapeutic effects through the mtDNA‐mediated ...
Jun Zhang   +8 more
wiley   +1 more source

HPLC-UV polyphenolic profiles in the classification of olive oils and other vegetable oils by principal component analysis [PDF]

open access: yes, 2016
HPLC-UV was applied to the analysis and characterization of olive oils and other vegetable oils. A chromatographic separation on a Zorbax Eclipse XDB-C8 reversed-phase column was proposed under gradient elution, employing 0.1% formic acid aqueous ...
Farrés-Cebrián, Mireia   +3 more
core   +2 more sources

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu   +10 more
wiley   +1 more source

A fast and sensitive isocratic high performance liquid chromatography method for determination of guaraná (Paullinia cupana) flavan-3-ols

open access: yesMethodsX, 2019
Most methods for quantification of catechins in guaraná and other food matrices rely on lengthy gradients to resolve all peaks, and the analysis time for one sample is around 45–135 min.
Lina Yonekura, Hirotoshi Tamura
doaj   +1 more source

Opportunities for topical antimicrobial therapy: permeation of canine skin by fusidic acid [PDF]

open access: yes, 2017
BACKGROUND: Staphylococcal infection of the canine epidermis and hair follicle is amongst the commonest reasons for antimicrobial prescribing in small animal veterinary practice.
A Loeffler   +29 more
core   +5 more sources

Bioorthogonal Photoactivation of 2‐Nitrobenzyl Caged Doxorubicin Anticancer Prodrugs on Gold Nanostars

open access: yesAdvanced Materials, EarlyView.
Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno   +15 more
wiley   +1 more source

Detection of benzimidazole carbamates and amino metabolites in liver by surface plasmon resonance-biosensor [PDF]

open access: yes, 2011
This research was funded by the Irish Department of Agriculture, Fisheries and Food under the Food Institutional Research Measure as part of the National Development Plan (Project 05/R&D/TN/355)peer-reviewedTwo surface plasmon resonance (SPR) biosensor ...
Brandon, David   +5 more
core   +1 more source

HPLC-UV Determination of Dextromethorphan in Syrup Method validation

open access: yesRevista de Chimie, 2019
A HPLC-UV method, for determination of dextromethorphan hydrobromide in syrup, was validated. The chromatographic analysis was performed using an RP-18, Nucleodur chromatographic column (250 mm 4 mm, 5 m) at constant temperature (50oC) with a mobile phase consisting of a mixture of acetonitrile/methanol (70:30 v/v) with sodium docusate (as ion pair
Nicolae Avram   +6 more
openaire   +1 more source

Water Permeates and Plasticizes Amorphous Carbon Dots: Unraveling the Inner Accessibility of the Nanoparticles by Glass Transition Studies

open access: yesAdvanced Materials, EarlyView.
The water permeability of amorphous carbon dots (CDs) is demonstrated by investigating their plasticization. Novel polyamide‐based and amorphous nanoparticles are synthesized by controlling their inner packing density. Water plasticization is evidenced by the decrease of the CDs glass transition temperature with increasing the hydration degree.
Elisa Sturabotti   +8 more
wiley   +1 more source

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