A low‐cost, portable point‐of‐care platform for rapid Mpox detection using loop‐mediated isothermal amplification is reported. The device integrates fluorescence readout and mobile monitoring. A machine‐learning model analyzes temperature data and correlates thermal changes with DNA concentration, enabling sensitive and reliable molecular diagnosis in ...
Nazente Atceken +4 more
wiley +1 more source
Photoenzymatic Hydroalkylation Enables Streamlined Access to Aryl Glutarimide Precursors
We report a photoenzymatic hydroalkylation that enables streamlined, stereocontrolled access to aryl glutarimide precursors relevant to targeted protein degradation. Engineered flavin‐dependent “ene”‐reductases provide broad scope and high enantioselectivity through a distinct electron transfer–enantioselective proton transfer pathway.
Zhi Xu +9 more
wiley +2 more sources
The Development and Validation of a Simple HPLC-UV Method for the Determination of Vancomycin Concentration in Human Plasma and Application in Critically Ill Patients. [PDF]
Aboelezz A +4 more
europepmc +1 more source
Extracción y cuantificación de cumarina mediante HPLC-UV en extractos hidroetanolico de semillas de Dipteryx odorata [PDF]
Alberto Oliveros‐Bastidas +4 more
openalex
Determination of Fluconazole in Children in Small Blood Volumes Using Volumetric Absorptive Microsampling (VAMS) and Isocratic High-Performance Liquid Chromatography-Ultraviolet (HPLC-UV) Detection. [PDF]
Zimbelmann F, Groll AH, Hempel G.
europepmc +1 more source
Synopsis. The [68Ga]GaIII‐TREN‐CAM radiochelate selectively accumulates in Gram‐negative sites of infection and noninvasively monitors treatment response a siderophore antibiotic. ABSTRACT Positron emission tomography (PET) is an emerging tool under clinical investigation for the detection of bacterial infections.
M. Andrey Joaqui‐Joaqui +6 more
wiley +2 more sources
Development of an HPLC-UV method for quantification of posaconazole in low-volume plasma samples: design of experiments and machine learning models. [PDF]
Bayat F +5 more
europepmc +1 more source
Chiral Heptagon‐Embedded Double [6]Helicenes via Scholl Reaction
One bond makes the difference–two chiral and twisted polycyclic aromatic hydrocarbons (PAHs) show different emission behavior. The more flexible one (top) shows a double emission with one having a large anti‐Stokes shift. The two peaks are assigned to different conformers of one and the same compound.
Dan Wang +6 more
wiley +2 more sources

