Performance of the Roche Total Mycophenolic Acid® assay on the Cobas Integra 400®, Cobas 6000® and comparison to LC-MS/MS in liver transplant patients [PDF]
Background: Mycophenolic acid (MPA) is an immunosuppressant for which therapeutic drug monitoring (TDM) is performed for optimal prophylaxis and avoidance of toxicity in transplant patients.
Decavele, An-Sofie +3 more
core +1 more source
Determination of Fucoxanthin in Bloom-Forming Macroalgae by HPLC–UV
Abstract Fucoxanthin is a carotenoid natural product with extensive biological activities and offers a variety of health benefits. Brown algae and diatoms are known producers of this compound as an important component of their light-harvesting complexes.
Minlan, Li +3 more
openaire +2 more sources
Microwave Assisted Synthesis of Py-Im Polyamides [PDF]
Microwave synthesis was utilized to rapidly build Py-Im polyamides in high yields and purity using Boc-protection chemistry on Kaiser oxime resin. A representative polyamide targeting the 5′-WGWWCW-3′ (W = A or T) subset of the consensus Androgen and ...
Bacsa B. +38 more
core +2 more sources
Analysis of imidazoles and triazoles in biological samples after MicroExtraction by packed sorbent [PDF]
This paper reports the MEPS-HPLC-DAD method for the simultaneous determination of 12 azole drugs (bifonazole, butoconazole, clotrimazole, econazole, itraconazole, ketoconazole, miconazole, posaconazole, ravuconazole, terconazole, tioconazole and ...
Bellagamba, Giuseppe +9 more
core +3 more sources
Quantification of Plasma and Urine Thymidine and 2'-Deoxyuridine by LC-MS/MS for the Pharmacodynamic Evaluation of Erythrocyte Encapsulated Thymidine Phosphorylase in Patients with Mitochondrial Neurogastrointestinal Encephalomyopathy. [PDF]
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an ultra-rare disorder caused by mutations in TYMP, leading to a deficiency in thymidine phosphorylase and a subsequent systemic accumulation of thymidine and 2'-deoxyuridine.
Antunes, NJ +8 more
core +1 more source
A rapid and sensitive method for the detection of protocatechuic acid (PA), chlorogenic acid (CLA) and caffeic acid (CAA) has been developed by high-performance liquid chromatography (HPLC) with an ultraviolet detector (UV) and an electrochemical ...
Zhongyin Zhang +5 more
doaj +1 more source
Cloud point extraction of Δ9-tetrahydrocannabinol from cannabis resin [PDF]
A cloud point extraction coupled with high performance liquid chromatography (HPLC/UV) method was developed for the determination of Δ9-tetrahydrocannabinol (THC) in micellar phase.
Ameur, Soumia +4 more
core +2 more sources
The microbiological bioassay, UV-spectrophotometry and HPLC methods for assaying gatifloxacin in tablets were compared. Validation parameters such as linearity, precision, accuracy, limit of detection and limit of quantitation were determined. Beer's law
Cristiani Capistrano Gonçalves de Oliveira Lopes +1 more
doaj +1 more source
Abrus precatorius is a leguminous plant with high medicinal value. Its leaves are rich in flavonoids. There only are limited reports on the extraction process and quality assessment of total flavonoids in Abrus precatorius leaves (APL).
Xujiang Yuan +4 more
doaj +1 more source
Validation of HPLC–UV Assay of Caffeic Acid in Emulsions [PDF]
An accurate, sensitive, precise and rapid reversed-phase high-performance liquid chromatographic method was successfully developed and validated for the determination of caffeic acid (CA) in emulsions. The best separation was achieved on a 250 × 4.6 mm, 5.0 µm particle size RP18 XDB Waters column using ethanol and purified water (40:60 v/v) adjusted to
Spagnol, Caroline Magnani +3 more
openaire +3 more sources

