Results 121 to 130 of about 964,371 (305)

Bioorthogonal Photoactivation of 2‐Nitrobenzyl Caged Doxorubicin Anticancer Prodrugs on Gold Nanostars

Advanced Materials, EarlyView.
Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno, Andrea Escudero, Oscar Ferreira Silvestre, José Manuel Terrés, Mónica Gorbe, Eva Garrido, Carlos Renero‐Lecuna, Judith Langer, María Alfonso, Javier Ibañez, Félix Sancenón, Roberto Cao‐Milán, Luis M. Liz‐Marzán, Alba García‐Fernández, Andy Hernández‐Montoto, Ramón Martínez‐Máñez   +15 more
wiley   +1 more source

Mebendazole spectrophotometric determination: theorical and experimental study of the interaction with sodium hydroxide [PDF]

, 2016
USP, EP, and Argentinian Pharmacopoeia proposed HPLC-UV for quantitative quality control of mebendazole (MBZ) tablets. In this work, a spectrophotometric method is proposed.
Delfino, Mario Raul, Jorge, Nelly Lidia, Monzón, Celina María, Sarno, María del Carmen Teresa   +3 more
core  

Water Permeates and Plasticizes Amorphous Carbon Dots: Unraveling the Inner Accessibility of the Nanoparticles by Glass Transition Studies

Advanced Materials, EarlyView.
The water permeability of amorphous carbon dots (CDs) is demonstrated by investigating their plasticization. Novel polyamide‐based and amorphous nanoparticles are synthesized by controlling their inner packing density. Water plasticization is evidenced by the decrease of the CDs glass transition temperature with increasing the hydration degree.
Elisa Sturabotti, Valerio Di Lisio, Lucia Cardo, Alessandro Camilli, Estela Moretón Alfonsín, Daniele Cangialosi, Amaia Iturrospe Ibarra, Arantxa Arbe, Maurizio Prato   +8 more
wiley   +1 more source

Electrically Readable Lateral Flow Assay Using Organic Transistors for Diagnostic Applications

Advanced Materials, EarlyView.
Electrolyte‐gated organic field‐effect transistors (EGOFETs) are integrated with lateral flow (LF) paper fluidics to create a reusable, portable, and low‐cost point‐of‐care (PoC) diagnostic test. The devices are validated for Human Immunoglobulin G detection, achieving high sensitivity (0.1 fm), selectivity, and reproducibility with rapid results in 20–
María Jesús Ortiz‐Aguayo, Carme Martínez‐Domingo, Diego Gutiérrez, Dean Kos, Marta Mas‐Torrent   +4 more
wiley   +1 more source

Phytochemical and physicochemical studies of different apple varieties grown in Morocco

Open Chemistry
The apple is an important part of the human diet and is one of the most popular fruits in Morocco, with varieties that are now suitable for human consumption.
Mohammed Kara, Saghrouchni Hamza, El Abdali Youness, Amine Assouguem, Haoudi Nouha, El fadili Mohamed, Amar Aya, Hamijo Tareq, Var Isil, Ullah Riaz, Rachid Zerhouni Abdou, Jamila Bahhou   +11 more
doaj   +1 more source

Azaporphyrinoid‐Based Photo‐ and Electroactive Architectures for Advanced Functional Materials

Advanced Materials, EarlyView.
A long‐standing collaboration between the Torres and Guldi groups has yielded diverse azaporphyrinoid‐based donor‐acceptor nanohybrids with promising applications in solar energy conversion. This conspectus highlights key molecular platforms and structure‐function relationships that govern light and charge management, supporting the rational design of ...
Jorge Labella, Kobra Azizi, Dirk M. Guldi, Tomás Torres   +3 more
wiley   +1 more source

Development and Validation of an Analytical Procedure for the Determination of Caffeic Acid in Nonea rossica Herb by HPLC

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. According to the literature, alcoholic extracts of Nonea rossica Steven have anticoagulant, antimicrobial, and antifungal properties, which may be due to the presence of caffeic acid and its derivatives in the plant.
V. V. Velichko, A. V. Lastovka, M. E. Kartashova, A. A. Gaiduk, D. S. Kruglov   +4 more
doaj   +1 more source

A Biochar‐Based Composite Hydrogel Microenvironment for Enhanced Biocatalysis

Advanced Materials, EarlyView.
This work presents the synthesis of a polyacrylamide hydrogel wherein biomass‐derived biochar is co‐encapsulated with the enzyme horseradish peroxidase (HRP). The resulting composite hydrogel possesses balanced electron‐rich and electron‐deficient domains, creating an optimal microenvironment that concentrates both hydrogen peroxide and phenol ...
Shengzhe Wang, Jingling Zhu, Weiyang Xue, Yuting Wen, Zhongxing Zhang, Xia Song, Yuan Yu, Chenglin Sun, Huangzhao Wei, Jun Li   +9 more
wiley   +1 more source

Quantitative Determination of Major Active Components in Polymyxin B Medicinal Products by NMR Spectroscopy

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Polymyxin B is a natural multicomponent antibiotic used in its sulfate form for the treatment of infections caused by multidrug-resistant Gram-negative bacteria. Pharmacopoeial standards for polymyxin B medicinal products include limits for
N. E. Kuz’mina, S. V. Moiseev, I. Yu. Yakupov, S. I. Kuleshova   +3 more
doaj   +1 more source

Solvent‐Mediated Reactivity Control of Lewis‐Paired Dopants as a Versatile Strategy for Tunable and Stable Doping of Organic Semiconductors

Advanced Materials, EarlyView.
Solvent‐mediated reactivity control of Lewis‐paired dopants enables highly efficient, finely tunable, and stable doping of organic semiconductors. The optimally doped semiconductor films exhibit superior thermoelectric performance and doping stability, feature delocalized polarons along structurally ordered polymer backbones, and outperform ...
Sang Beom Kim, Eui Hyun Suh, Taek Seong Lee, Andreas W. Erhardt, Iain McCulloch, Jaeyoung Jang   +5 more
wiley   +1 more source