Results 121 to 130 of about 576,132 (255)

Shared Extracellular Matrix Remodeling and Proteomic Signature in Dupuytren's Disease and Relapsed Clubfoot Tissue. [PDF]

Cells
Novotny T, Eckhardt A, Knitlova J, Doubkova M, Stachon R, Hrdina F, Kobets T, Ostadal M.   +7 more
europepmc   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Studies of hexahelicene bonded phases for the HPLC resolution of enantiomers [PDF]

The thesis presents a review of the literature on the HPLC resolution of enantiomers using chiral stationary phases and discusses the mechanisms of separation and the utility of these phases.
Del Alamo, Aurora
core  

From Conventional Methods to Innovation: Caffeine and Chlorogenic Acid Extraction and Quantification in the Rise of Smart and Green Techniques-A Systematic Review. [PDF]

Molecules
Awwad SH, Nasereddin LM, Al-Tamimi O, Daraosheh AQ, Elrashidi A, Abu Al-Shayeb L, Shannag M, Mohammad BA, Issa R, Abu-Samak MS.   +9 more
europepmc   +1 more source

Atroposelective Access to π‐Conjugated 1,2‐Azaborepines Enabled by Palladium‐Catalyzed Cyclization of N‐Heterobiaryls with Alkynylboronates

Advanced Science, EarlyView.
We report a palladium‐catalyzed atroposelective cyclization of N‐heterobiaryl triflates with alkynyl boronates to access seven‐membered 1,2‐BN‐bridged biaryls with high yields and excellent enantioselectivity via a cascade DyKAT, cis‐carbopalladation, and 1,2‐migration, which expands the toolbox for axially chiral π‐conjugated boron compounds and opens
Fengya He, Zhen Wang, Haoyu Guo, Shuguang Chen, Xu Zhang, Yongjia Shang, Hui Wang   +6 more
wiley   +1 more source

A Unified Analytical Method Greenness Score (<i>uAMGS</i>) Quantifies How Microscopic Imaging Is Greener Than Conventional Liquid Chromatography. [PDF]

ACS Sustain Chem Eng
Inaba K, Monge Neria R, Saylor RA, Kisley L.   +3 more
europepmc   +1 more source

Targeting ANGPTL3 and IL‐33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis

Advanced Science, EarlyView.
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li, Zhonglian Cao, Rongrui Zhou, Xu Cheng, Xiaozhi Hu, Shuwen Xu, Zihan Dou, Ling Du, Dianwen Ju   +8 more
wiley   +1 more source

Comparative evaluation of ELISA, PPIA, and HPLC/MS for microcystin quantification in seven lakes of western Michigan. [PDF]

Front Microbiol
Cheng C, Tang X, Cai Y, Deng D, Xie L, Rediske RR.   +5 more
europepmc   +1 more source

Dual‐Substrate Synergistic Photocatalysis: Exogenous Reagent‐Free Co‐Removal of Phenol and Cr(VI) via Electron‐Donor‐Mediated Redox Coupling over Modified Carbon Nitride

Advanced Science, EarlyView.
An exogenous reagent‐free dual‐substrate strategy harnesses phenol as an intrinsic electron donor to drive synchronous phenol degradation and Cr(VI) reduction over modified carbon nitride. π–π stacking and hydrogen bonding direct electron transfer to the catalyst, enriching photogenerated electrons and accelerating Cr(VI) reduction 6.4‐fold. This waste‐
Xiaoman Zhang, Qiyu Wang, Xiaodan Liu, Shuqi Wan, Cuiwei Du, Qilu Li, Chongfei Yu, Shuying Dong, Xianfa Su, Chun Hu   +9 more
wiley   +1 more source

Diagnostic Utility of High-Performance Liquid Chromatography and Its Correlation With Hematological Indices in the Evaluation of Hemoglobinopathies. [PDF]

Cureus
Sharma R, Khayyam N, Sharma SP, Gupta YK, Sharma V.   +4 more
europepmc   +1 more source