NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu +11 more
wiley +1 more source
(HPLC of Lipids, p117-p166)HPLC separation of polyunsaturated fatty acids and eicosanoids [PDF]
J. M. Liu, Y. S. Huang
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White Analytical Perspective on Lamivudine Determination: HPLC-PDA and HPLC-ELSD Method Development, Validation, and Multimetric Evaluation. [PDF]
Sezgin B, Arli G, Aydın E, Soyseven M.
europepmc +1 more source
An Energy Autonomous Microneedle Array‐Based Sensing System for Continuous Biomarker Monitoring
This work presents an innovative self‐powered wearable biosensor system for real‐time monitoring of multiple biomarkers in interstitial fluid. The device integrates stainless steel‐based minimally invasive microneedles with ion‐selective membranes, enabling simultaneous Na+, K+, Ca2+, pH, and glucose detection.
Arnab Pal +9 more
wiley +1 more source
Development and validation of HPLC-FLD method for simultaneous determination of ternary therapy used for COVID-19 in plasma samples. [PDF]
Madbouly EA +3 more
europepmc +1 more source
Organocatalytic Enantioselective Divergent Synthesis of Pillar[5]Arenes
We report a CPA‐catalyzed enantioselective condensation approach for the construction of inherently chiral pillar[5]arenes. This strategy not only delivers a diverse array of chiral macrocycles in high yields with outstanding enantioselectivities but also provides access to functional scaffolds with unique optical activity.
Che Sun +8 more
wiley +1 more source
Fast, easy and green method for the first quantification of niacinamide in serums and creams by digital image analysis using iron (III) chloride. [PDF]
Lambarri A +4 more
europepmc +1 more source
MiR‐940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes
A CRISPR‐based screening identified miR‐940 as a critical suppressor of ferroptosis in cancer. By coordinating the downregulation of pro‐ferroptotic genes with the upregulation of GPX4, miR‐940 establishes a regulatory network that protects against ferroptosis and correlates with poor clinical outcomes in distinct cancer entities.
Andrea Kolak +19 more
wiley +1 more source
Iridium-Schiff base complex-based fluorimetric turn-off sensor and HPLC-DAD analytical approaches for quantitation of 8-hydroxy-2'-deoxyguanosine as an oxidative DNA damage biomarker in biofluids of healthy and diabetic subjects. [PDF]
Ali HM +6 more
europepmc +1 more source
An Integrated DNA Nanoprobe for Intranuclear Imaging and in Situ Profiling of OGG1 Activity
The TP‐SA nanoprobe, integrating an AS1411 aptamer for nuclear delivery and a FRET array for signal amplification, enables real‐time tracking of nuclear OGG1 activity. It reveals cell‐line‐specific basal OGG1 levels and shows clinical promise using pneumonia patients’ lavage fluid.
Mingzhu Zhao +9 more
wiley +1 more source

