Results 221 to 230 of about 964,371 (305)

Identification of Quality Markers in Viola kunawaresis Royel Using HPLC Fingerprints, Chemometric Analysis, and Network Pharmacology. [PDF]

Biomed Chromatogr
Liu H, Zhao R, Xu H, Manaer T, Pan L, Jin L, Ayupbek A.   +6 more
europepmc   +1 more source

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy, Zoe L. Chau, Sheng‐You Chen, Nanami Fujisawa, John J. Hill, Barnett M. Hsu, Joanne K. Liu, Karol W. Mai, James J. Lai   +8 more
wiley   +1 more source

Polar Lattice‐Distorted Motifs Enable Synergy of Local Polarization/Dipole Fields for Concurrent Glyphosate Wastewater Remediation and CO Evolution

Advanced Science, EarlyView.
Photocatalytic treatment of glyphosate herbicide in agricultural wastewater is achieved through the cooperative effect of the local polarization field and dipole field mediated by lattice‐distorted carbon nitride. Glyphosate is completely degraded via selective C─P bond cleavage with a CO evolution rate of 1166 µmol g−1 h−1.
Daoping Chen, Huan Liu, Tengyu Liu, Jie Li, Qizhi Luo, Yan Zhang, Shengkun Li, Hu Li   +7 more
wiley   +1 more source

Multifactorial Perspective for Greening Solid-Phase Peptide Synthesis: Rigid Polyacrylate Macroporous Resin in Combination with Green Solvents. [PDF]

ChemSusChem
Noki S, Kumar A, Zhang C, Basso A, Serban S, Kou X, Li Y, Sharma A, de la Torre BG, Albericio F.   +9 more
europepmc   +1 more source

A Mitochondria‐Specific Nanomedicine for Synergistic Chemo‐Photothermal Therapy and Immunogenic Activation Against Breast Cancer

Advanced Science, EarlyView.
Peptide dendrimer–based nanoplatform with mitochondria‐targeting capability was developed for synergistic chemo‐photothermal therapy. The system promotes efficient transcytosis, induces mitochondrial dysfunction, triggers immunogenic cell death (ICD), and enhance antitumor immunity by promoting dendritic cell maturation and T‐cell activation, resulting
Min Li, Jiangqi Feng, Junyang Zhuang, Qingguo Zhong, Yanda Li, Yanzhuo Lv, Shaoteng Huang, Xiangyu Huang, Mingbo Zhang, Xiaofeng Cai, Yuxin Wang, Wenping Chen, Zhenyu Duan, Zhou Chen, Kui Luo, Ning Li   +15 more
wiley   +1 more source

Development and validation of a novel analytical method for related substances of resmetirom and identification of new degradation products. [PDF]

Front Chem
Qin J, Luo Q, Wu W, Wang Q, Cai L, Wang S, Zhu Y.   +6 more
europepmc   +1 more source

An ATP‐Mediated Antibiotic β‐Peptide Nanofiber That Kills Multidrug‐Resistant Bacteria via a Multistage Mechanism

Advanced Science, EarlyView.
The 3K‐AP system forms infinite supramolecular fibrils that undergo controlled degradation into shorter fragments upon enzymatic hydrolysis. Multitechnique imaging reveals a stepwise bacteriolytic mechanism involving bacterial entrapment, disassembly into lethal constructs, and associated extracellular vesicle release, highlighting the dynamic ...
Sohini Chakraborty, Kamal el Battioui, Dániel Molnár, Bálint Jezsó, Lejla Daruka, Tasvilla Sonallya, Tünde Juhász, Rita Hirmondó, Imola Cs. Szigyártó, Loránd Románszki, Natália Tőkési, Daniel Pinkas, Eszter Házy, Olivér Pavela, Andrea Bodor, Zoltán Varga, István Mándity, Mihály Kovács, Csaba Pál, Kata Horváti, Judit Tóth, Tamás Beke‐Somfai   +21 more
wiley   +1 more source

Development and Validation of an Isocratic HPLC Method for the Simultaneous Determination of Avobenzone and Tris-Biphenyl Triazine. [PDF]

ACS Omega
Miranda JA, da Cruz YF, Alencar ÉN, Oliveira WN, Soares DCF, Donovan MD, Egito EST.   +6 more
europepmc   +1 more source

m5C‐Modified tRF3b‐CysGCA‐23 Suppresses Bladder Cancer Malignancy by Repressing H3K18 Lactylation via Stabilizing RBM4

Advanced Science, EarlyView.
In this study, we identified an NSUN6‐dependent m5C‐modified tsRNA, m5C‐tRF3b CysGCA‐23 (mtRC), that is downregulated in BC and inversely correlated with disease progression. Mechanistically, mtRC suppresses BC malignancy by stabilizing RBM4, attenuating glycolysis, and thereby limiting H3K18 lactylation–mediated activation of IL1RAP and VASH2 ...
Xiaoling Ying, Yapeng Huang, Jian Huang, Qinyu Cai, Danni Zhang, Cong Chen, Yuxi Nie, Baotong Yang, Chuan Li, Wenyu Hu, Chang Xiong, Chengcheng Zhang, Ding Ji, Yaomin Liang, Mei Yang, Wenqi Wu, Weidong Ji   +16 more
wiley   +1 more source