A stability-indicating LC method was validated for the quantification of midazolam (MDZ) active pharmaceutical ingredient (API) and in pharmaceutical formulations. Isocratic chromatography was performed on C18 column with mobile phase containing methanol/
Daiane Anzilaggo+4 more
doaj +1 more source
Analysis of imidazoles and triazoles in biological samples after MicroExtraction by packed sorbent [PDF]
This paper reports the MEPS-HPLC-DAD method for the simultaneous determination of 12 azole drugs (bifonazole, butoconazole, clotrimazole, econazole, itraconazole, ketoconazole, miconazole, posaconazole, ravuconazole, terconazole, tioconazole and ...
Campestre, Cristina+9 more
core +1 more source
Alkaloids from the Sponge Stylissa carteri Present Prospective Scaffolds for the Inhibition of Human Immunodeficiency Virus 1 (HIV-1). [PDF]
The sponge Stylissa carteri is known to produce a number of secondary metabolites displaying anti-fouling, anti-inflammatory, and anti-cancer activity. However, the anti-viral potential of metabolites produced by S.
Bader, Theresa Maria+7 more
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The present study reports the development and validation of a microbiological assay. To assess this methodology, the method was developed and validated for the quantification of CEF by high performance liquid chromatography (HPLC).
Idamir José Mascarello Junior+4 more
doaj +1 more source
Liquid chromatography metabolite profiling of tenofovir disoproxil fumarate [PDF]
Reverse transcriptase inhibitors are the most frequently prescribed agents for HIV infections. This publication presents a validated, highly sensitive and selective isocratic HPLC method for the quantitative determination of tenofovir disoproxil fumarate
Kokil Sachin, Bhatia Manish
doaj
Resorcinol and 4-n-butyl resorcinol have been used to improve skin health. However, these two compounds were unstable due to the oxidation process. Lipid nanoparticle formulation strategies were reported as the solution to overcome the stability problem ...
Rini Dwiastuti+3 more
doaj +1 more source
Stability of Extemporaneously Prepared Rufinamide Oral Suspensions [PDF]
Background: Rufinamide is an oral antiepileptic drug indicated for adjunctive therapy in treating generalized seizures associated with Lennox-Gastaut syndrome. Currently, rufinanide is available as 200-mg and 400-mg tablets. A liquid dosage form does not
Best, Robert+3 more
core +2 more sources
A COMPARATIVE STUDY ON THE CONCENTRATIONS OF TCMTB BASED FUNGICIDES IN LEATHER AND THEIR EFFECT ON MOULD RESISTANCE [PDF]
TCMTB (2-(thiocyanomethylthio)-benzothiazole), as a broad spectrum antifungal agent, has found a wide spread usage in processing of pickled, wet-blue and crust leathers and became one of the most used fungicides in leather although it suffered some ...
POLATDEMIR Erdogan Can+2 more
doaj
Tuberculosis in Dr Granville's mummy: a molecular re-examination of the earliest known Egyptian mummy to be scientifically examined and given a medical diagnosis [PDF]
‘Dr Granville's mummy’ was described to the Royal Society of London in 1825 and was the first ancient Egyptian mummy to be subjected to a scientific autopsy.
Abu Al-Soud W.+15 more
core +2 more sources
Comprehensive measurement of purines in biological samples
Defects in numerous aspects of purine metabolism are well-recognized causes for human diseases. The applicability of ultra performance liquid chromatography (UPLC) with photodiode array (PDA) detection for analysis of the most abundant biological ...
Rong Fu+6 more
doaj +1 more source