Results 51 to 60 of about 607,274 (305)

Determination of technological parametrs and good quality of phyto-tea based on medicinal peony (Paeonia officinalis l.) [PDF]

open access: yesBIO Web of Conferences
Plants of the genus Paeonia are considered promising sources of natural sedatives. Primarily, roots and rhizomes are used as medicinal raw materials for the treatment of neurasthenia, neurosis, hypochondria, and insomnia.
Zuparova Zulfia   +5 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

The Pharmacokinetic Profile of Freeze-dried Cyclosporine A-Eudragit S100 Nanoparticle Formulation in Dogs

open access: yesNano Biomedicine and Engineering, 2011
The pharmacokinetic profile of freeze-dried cyclosporine A-Eudragit S100 nanoparticles (CyA-S100-NP)was studied with a random two-way crossover study in dogs.
Yang Liu   +5 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Examination of the optical purity of voriconazole on the brush-type stationary phase [PDF]

open access: yesKragujevac Journal of Science
The purpose of this research is to develop an HPLC method for determining the content of voriconazole enantiomers in powder for solution for infusion. Chromatographic analysis was conducted using a brush-type (Pirkle-type) stationary phase with isocratic
Turković Nemanja M.   +3 more
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

HPLC-MS/MS pooled samples

open access: yes, 2018
HPLC-MS/MS runs of pooled MeOH extracts from Philanthus, Trachyous and Philanthunus specimen antennae and ...
Kai, Marco   +11 more
core   +1 more source

Changes in various secondary metabolites by crossing modern rose cultivars

open access: yesFolia Horticulturae
The aim of the study was to determine the content and composition of phenolic compounds in autochthonous rose hips (R. pendulina, R. spinosissima and R.
Kunc Nina   +3 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy