Results 61 to 70 of about 607,274 (305)

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

HPLC módszerfejlesztés

, 2019
A szakdolgozatomat az Alkaloida Vegyészeti Gyár Zrt Minőségellenőrzésének a kromatográfiás egységénél végeztem. A kitűzött célom az volt, hogy a venlafaxine tabletta hatóanyag tartalmát, mind a minta előkészítést, mind a HPLC mérést környezetkímélően és ...
Halász, Andrea
core  

Determination of Irbesartan in Pharmaceutical Preparations by HPLC

Cumhuriyet Science Journal
In this study, a high-performance liquid chromatography (HPLC) method was developed to analyze irbesartan in both pure and pharmaceutical formulations. The mobile phase consisted of an acetonitrile-1.0 mM potassium dihydrogen phosphate solution (30:70, v/
Bilal Yılmaz
doaj   +1 more source

Dipole‐Engineered Conductive Additives for Ultrastable Interphase Evolution in High‐Areal‐Capacity Silicon Anodes

Advanced Functional Materials, EarlyView.
In the work reported herein, dipole‐engineered sulfonated carbon nanofibers enable conductive additives to actively regulate interphase formation in silicon anodes. Polar sulfonyl groups guide electrolyte decomposition to form a compact LiF‐rich interphase while promoting robust integration with silicon.
Song Kyu Kang, Hyeonju Kim, Jeongbin Cho, Minseon Park, Taehun Kim, Seonghun Sin, Won Bae Kim   +6 more
wiley   +1 more source

HPLC Method Development for Pharmaceuticals.

, 2007
High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control ...

core  

Sensitive Analysis of Epilepsy Drug, Phenobarbital, Based on Column Type Solid Phase Extraction and HPLC-DAD System

Cumhuriyet Science Journal
An analytical approach has been developed for the sensitive determination of Phenobarbital, which is used as an antiepileptic drug molecule. The analysis of this active molecule, which has a very limited study even for its direct determination in the ...
Seren Kilit, Esra Durgun, Aslıhan Gürbüzer, Elif Tümay Özer, Bilgen Osman, Ümmügülsüm Polat, Halil İbrahim Ulusoy   +6 more
doaj   +1 more source

Engineering Pendant Group Chemistry to Control Hydrophilicity and Oxidative Degradation of Thioketal‐Based Biomaterials

Advanced Functional Materials, EarlyView.
Thioketal (TK) polymers are promising biomaterials due to their selective biodegradation by reactive oxygen species (ROS), but they respond slowly to physiologic doses of ROS. Here, the TK bond's pendant groups are modified to enhance the degradation of TK‐based implants both in vitro and in vivo.
Karina A. Bruce, Dylan W. Marques, Alan J. Fullenkamp, Emma‐Louise Lowell, Rais B. Fataki, Jake D. Ryan, John R. Martin   +6 more
wiley   +1 more source

HPLC In Chiral Pharmaceutical Analysis

, 2011
High performance liquid chromatography (HPLC) is one of the most widespread analytical and preparative scale separation techniques used for both scientific investigations and industrial and biomedical analysis. Now in its second edition, this revised and
Pettersson, Curt,, Hedeland, Ylva,
core  

Molecular docking studies of anti-inflammatory, antioxidant activity and phytochemical composition of Rubus idaeus shoot extract

Annals of Mechnikov's Institute
Introduction. Currently, the primary treatments for inflammation include steroidal drugs (e.g., prednisolone) and non-steroidal anti-inflammatory drugs (NSAIDs) such as diclofenac and indomethacin, which are widely used to manage both acute and chronic ...
Oleksandr Maslov, Darina Horopashna, Mykola Komisarenko, Sergii Kolisnyk, Lyudmyla Derymedvid, Andrey Komisarenko, Olga Antonenko   +6 more
doaj   +1 more source

Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review

Advanced Functional Materials, EarlyView.
Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera, Chiranjeevi Kanike, Appurva Tiwari, Hongyan Wu, Larry D. Unsworth, Ben Bin Xu, Xuehua Zhang   +6 more
wiley   +1 more source