Results 191 to 200 of about 16,314 (232)
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Effect of HPMC concentration on β-cyclodextrin solubilization of norfloxacin
Carbohydrate Polymers, 2014The effect of hydroxypropyl methylcellulose (HPMC) concentration on β-cyclodextrin (β-CD) solubilization of norfloxacin was examined. The solubility and dissolution of norfloxacin/β-CD and norfloxacin/β-CD/HPMC inclusion complexes were studied. The presence of β-CD increased significantly the solubility and dissolution of norfloxacin.
Gabriel Onn Kit Loh, Kok Khiang PEH
exaly +3 more sources
Food Hydrocolloids, 2008
Mackerel nuggets used in this study were coated with HPMC prior to battering or coated with batter containing HPMC in order to improve crust crispness through the formation of a thermal gel barrier preventing the diffusion of water from meat into the crust during microwave reheating.
Hui-Huang Chen
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Mackerel nuggets used in this study were coated with HPMC prior to battering or coated with batter containing HPMC in order to improve crust crispness through the formation of a thermal gel barrier preventing the diffusion of water from meat into the crust during microwave reheating.
Hui-Huang Chen
exaly +2 more sources
Methylcellulose (MC) and Hydroxypropylmethylcellulose (HPMC)
2022Methylcellulose was one of the earliest synthetic substitutes for natural gums in food applications. In addition to use in the food industry, both methylcellulose and hydroxypropylmethylcellulose find broad application in a variety of industrial and pharmaceutical uses, including the construction, coatings, chemical, cosmetics, and textile industries ...
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HPMC- A Marvel Polymer for Pharmaceutical Industry-Patent Review
Recent Advances in Drug Delivery and Formulation, 2021At the present time, designing of defined release dosage forms, either controlled, sustained, modified, are gaining much importance. For the development of such delivery systems, proper blend of polymers is required so that drug release occurs by polymer erosion, swelling, diffusion/ dissolution.
Kumar Guarve, Priyanka Kriplani
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International Journal of Pharmaceutics, 1996
Abstract The effects of hydroxypropylmethylcellulose (HPMC) moisture content on the properties of tablets made with HPMC as base excipient were investigated. Two varieties of HPMC, with nominal viscosities of 4000 and 100 000 cP, were evaluated. The drug model used was hydrochlorothiazide, present in tablets at 1% w/w.
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Abstract The effects of hydroxypropylmethylcellulose (HPMC) moisture content on the properties of tablets made with HPMC as base excipient were investigated. Two varieties of HPMC, with nominal viscosities of 4000 and 100 000 cP, were evaluated. The drug model used was hydrochlorothiazide, present in tablets at 1% w/w.
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Molecular Pharmaceutics, 2016
Sodium lauryl sulfate (SLS), as an effective surfactant, is often used as a solubilizer and/or wetting agent in various dosage forms for the purpose of improving the solubility and dissolution of lipophilic, poorly water-soluble drugs. This study aims to understand the impact of SLS on the solution behavior and bioavailability of hypromellose acetate ...
Yuejie, Chen +9 more
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Sodium lauryl sulfate (SLS), as an effective surfactant, is often used as a solubilizer and/or wetting agent in various dosage forms for the purpose of improving the solubility and dissolution of lipophilic, poorly water-soluble drugs. This study aims to understand the impact of SLS on the solution behavior and bioavailability of hypromellose acetate ...
Yuejie, Chen +9 more
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Designing HPMC matrices with improved resistance to dissolved sugar
International Journal of Pharmaceutics, 2010High concentrations of dissolved sugars can accelerate in vitro drug release in certain hydroxypropyl methylcellulose (HPMC) matrices (Williams et al., 2009). This study investigated the potential for common formulation variables to modulate sucrose sensitivity, and explored if more resistant formulations could be designed. In a model matrix containing
Hywel D, Williams +4 more
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Comparison of vitreous replacement with Healon� and with HPMC in rabbits' eyes
Documenta Ophthalmologica, 1986Ten rabbits underwent vitreous aspiration and replacement by either Healon or Hydroxy Propyl Methyl Cellulose 2%. Four weeks' observation did not reveal noticeable differences between Healon and HPMC with regard to anterior chamber reaction, intra-ocular pressure or cataract.
R, Koster, J S, Stilma
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Journal of Applied Polymer Science, 2016
ABSTRACTMatrix tablets containing paracetamol and hydroxypropyl methylcellulose (HPMC 2906) of different viscosity grades (50, 400, 1500, and 4000 mPa·s) were evaluated for drug release and change in matrix tablet mass [ΔM (%)] after exposure to 0.09, 0.15, 0.31, and 0.52M ionic strengths of dissolution media.
Ana Krese +4 more
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ABSTRACTMatrix tablets containing paracetamol and hydroxypropyl methylcellulose (HPMC 2906) of different viscosity grades (50, 400, 1500, and 4000 mPa·s) were evaluated for drug release and change in matrix tablet mass [ΔM (%)] after exposure to 0.09, 0.15, 0.31, and 0.52M ionic strengths of dissolution media.
Ana Krese +4 more
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Isotonic Riboflavin and HPMC With Accelerated Cross-Linking Protocol
Cornea, 2014The aim of this study was to monitor corneal pachymetry changes during accelerated collagen cross-linking (CXL) for keratoconus while using isotonic riboflavin with HPMC.All consecutive patients who underwent CXL for progressive keratoconus, using accelerated protocol and isotonic riboflavin with HPMC, from December 2012 to September 2013 were included
Vandana, Jain +2 more
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