Results 41 to 50 of about 16,314 (232)

pH independent controlled release of verapamil hydrochloride using HPMC-alginate matrices & organic acids

Journal of Applied Pharmaceutical Research
Background: Verapamil HCl, a weakly basic drug, exhibits pH-dependent solubility that limits sustained-release formulation efficacy. This study developed controlled-release matrix tablets using HPMC, sodium alginate, and organic acids to achieve pH ...
R U Gaware, K Sarvanan, S L Jadhav
doaj   +1 more source

Fast Dissolving Sublingual Strips: A Novel Approach for the Delivery of Isosorbide Dinitrate [PDF]

Pharmaceutical Sciences, 2019
Background: Isosorbide dinitrate (ISDN) is used for treating the angina attacks. In addition, oral ISDN is available in immediate and sustained release formulations and the bioavailability of ISDN is about 20-25% when taken orally.
Marzieh Fathei, Mitra Alami-milani, Sara Salatin, Sharahm Sattari, Hassan Montazam, Farhad Fekrat, Mitra Jelvehgari   +6 more
doaj   +1 more source

XRD pattern of MLX (a), HPMC (b), physical mixture of MLX & HPMC (c), and optimized formulation (F0), (d).

, 2022
XRD pattern of MLX (a), HPMC (b), physical mixture of MLX & HPMC (c), and optimized formulation (F0), (d).
Sobia Noreen (8761776), Syed Abdul Wasay (12456381), Syed Umer Jan (12456384), Muhammad Akhtar (2271907), Rahman Gul (12456387)   +4 more
core   +1 more source

In vitro and in vivo Evaluation of the Efficacy and Safety of Powder Hydroxypropylmethylcellulose as Nasal Mucosal Barrier

Medical Devices: Evidence and Research, 2020
Todor A Popov,1 Jean Emberlin,2 Peter Josling,3 Alexander Seifalian4 1University Hospital Sv. Ivan Rilski, Department of Occupational Diseases, Sofia, Bulgaria; 2Allergy UK, Sidcup, Kent, UK; 3Herbal Research Centre, Battle, East Sussex, UK; 4NanoRegMed ...
Popov TA, Emberlin J, Josling P, Seifalian A   +3 more
doaj  

Development of Saturated Fat Replacers: Conventional and Nano-Emulsions Stabilised by Lecithin and Hydroxylpropyl Methylcellulose

Foods, 2022
The combination of two emulsifiers, lecithin and hydroxypropyl methylcellulose (HPMC), into emulsions is an interesting strategy to design fat replacers in food matrices.
Jansuda Kampa, Richard Frazier, Julia Rodriguez-Garcia   +2 more
doaj   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Allosteric Inhibition of Polycomb Repressive Complex 2 by an EZH2‐Selective Small Molecule Inhibitor

Advanced Science, EarlyView.
The study characterizes C36, a highly selective EZH2/PRC2 inhibitor that acts via a novel allosteric mechanism. Unlike previous inhibitors, C36 inhibits EZH2/PRC2 by disrupting the allosteric communication between EZH2 and EED in a SAM‐noncompetitive manner.
Ting Cao, Dongdong Liu, Haishan Gao, Chenyang Qin, Wen Zhang, Ziyun Lu, Dongxia Tan, Yuxiu Qu, Yusong Liu, Zhiran Zou, Hongtao Yu, Wei Qi   +11 more
wiley   +1 more source

DSC of MLX (a), HPMC (b), physical mixture of MLX as well as HPMC (c), and optimized formulation (F0), (d).

, 2022
DSC of MLX (a), HPMC (b), physical mixture of MLX as well as HPMC (c), and optimized formulation (F0), (d).
Sobia Noreen (8761776), Syed Abdul Wasay (12456381), Syed Umer Jan (12456384), Muhammad Akhtar (2271907), Rahman Gul (12456387)   +4 more
core   +1 more source

Dissolution Properties of Hydroxypropylmethylcellulose (HPMC) Capsules.

Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences), 2002
Dissolution tests of acetaminophen filled into the gelatin capsules (SHIONOGI QUALICAPS, Japan) and hydroxypropylmethylcellulose (HPMC) capsules (SHIONOGI QUALICAPS, Japan) were performed after the cap-sules were stored under conditions of 30°C/60%RH for one year, 40°C/75%RH for 6 months, or 60°C for one week.
Sakaeda, Toshiyuki, Nakamura, Tsutomu, Okumura, Katsuhiko, Tochio, Shinji, Nagata, Shunji   +4 more
openaire   +2 more sources

Controlled Nanoarchitecture of Aligned Electrospinning Fiber Composite Electrolyte Based on Plant and Animal Biopolymers for Safe Na‐Ion Batteries

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Aligned Electrospun Composite Electrolyte. The resurgence of solid‐state Na+ battery, sustained through lithium deficiency and mounting costs, offers an auspicious alternative to solid‐state Li+ battery. This study introduces a nanoarchitectural approach that integrates electrospinning with a simple solution casting technique to develop a mechanically ...
Md. Mehadi Hassan, Brett Conners, Mojtaba Ebrahimian Mashhadi, Jinguang Hu, Xia Li, Qingye Lu   +5 more
wiley   +1 more source