Results 31 to 40 of about 19,345 (178)

Fast Dissolving Sublingual Strips: A Novel Approach for the Delivery of Isosorbide Dinitrate [PDF]

open access: yesPharmaceutical Sciences, 2019
Background: Isosorbide dinitrate (ISDN) is used for treating the angina attacks. In addition, oral ISDN is available in immediate and sustained release formulations and the bioavailability of ISDN is about 20-25% when taken orally.
Marzieh Fathei   +6 more
doaj   +1 more source

In vitro and in vivo Evaluation of the Efficacy and Safety of Powder Hydroxypropylmethylcellulose as Nasal Mucosal Barrier

open access: yesMedical Devices: Evidence and Research, 2020
Todor A Popov,1 Jean Emberlin,2 Peter Josling,3 Alexander Seifalian4 1University Hospital Sv. Ivan Rilski, Department of Occupational Diseases, Sofia, Bulgaria; 2Allergy UK, Sidcup, Kent, UK; 3Herbal Research Centre, Battle, East Sussex, UK; 4NanoRegMed ...
Popov TA   +3 more
doaj  

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

open access: yesAdvanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song   +5 more
wiley   +1 more source

Atmospheric Water Harvesting Through Polymer Hydrogel Sorbents: Materials Chemistry, Design Strategies, and Applications

open access: yesAdvanced Science, EarlyView.
Polymer‐based hydrogels have emerged as promising materials for atmospheric water harvesting (AWH) due to their high water affinity, tunable network structure, and excellent moisture adsorption‐desorption performance. Functional hydrogel systems enable efficient water capture and controlled release under low‐energy conditions, offering a sustainable ...
Swagata Datta   +6 more
wiley   +1 more source

Extracellular Vesicles‐Based Biological Macromolecule Delivery Systems: Biogenesis, Characterization, and Emerging Clinical Applications

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu   +3 more
wiley   +1 more source

Alternative protein sources: Extraction, modification and strategies for developing sustainable high‐quality food products

open access: yesFood Biomacromolecules, EarlyView.
Novel Protein Sources: Strategies and Challenges for Product Formulation Abstract Search for alternative protein sources has intensified in the recent years, owing to the increasing population, demand for sustainable food systems and consumer's shift towards healthier diet choices.
Prem Sankaran   +4 more
wiley   +1 more source

The influence of fillers on theophylline release from clay matrices [PDF]

open access: yes, 2015
: The objectives of this study were to investigate the suitability of magnesium aluminium silicate (MAS) (Veegum®) to control drug release of a model drug, theophylline, from tablet matrices.
Asare-Addo, Kofi   +2 more
core   +1 more source

Penetrasi Natrium Diklofenak Sistem Niosom Span 20-Kolesterol Dalam Basis Gel HPMC 4000 [PDF]

open access: yes, 2012
The present study was designed to determine characteristic and penetration of diclofenac sodium in niosomal system which had been prepared in hidroxypropylmethyl cellulosa (HPMC) 4000 gel.
Noorma Rosita   +2 more
core   +1 more source

Spatially Resolved Metabolomics of Optimal Cutting Temperature (OCT) Compound‐Embedded Tumors

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Mass spectrometry imaging (MSI) is emerging as a powerful tool for uncovering the distribution of metabolites in the tumor microenvironment and studying tumor metabolism in vivo. To date, MSI of biobanked tissues contextualized by patient data has been limited to peptides, proteins, and glycans—with few examples for metabolites.
Joseph Monaghan   +6 more
wiley   +1 more source

Nanoparticles of Lovastatin: Design, Optimization and in vivo Evaluation

open access: yesInternational Journal of Nanomedicine, 2020
Dalia A Gaber1,2 1Department of Quality Control & Quality Assurance, Holding Company for Biological Products and Vaccines, Cairo, Egypt; 2Department of Pharmaceutics, College of Pharmacy, Qassim University, Buraidah, Saudi ArabiaCorrespondence: Dalia
Gaber DA
doaj  

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