Results 191 to 200 of about 31,176 (296)

Scientific Philosophy: Past and Future, 13 April

The Reasoner, 2010
Jonah N. Schupbach
doaj  

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

Citizen science reveals temporally structured insect attraction and mitigation efficacy under artificial light at night. [PDF]

Commun Biol
Reinhard JE, Dietenberger M, Rehberg H, Hofmann R, Lühr PE, Loubies von Harpe N, Vogel LN, Wächter T, Schroer S, Jechow A, Hölker F.   +10 more
europepmc   +1 more source

Probabilistic Computing via Gate‐Tunable Random Telegraph Noise

Advanced Science, EarlyView.
Intrinsic random telegraph noise in metal–oxide–semiconductor field‐effect transistors is harnessed to create gate‐tunable probabilistic bits. By modulating carrier‐trapping dynamics, the device produces stochastic binary outputs with a continuous bias‐to‐probability transfer.
Gyungwon Yun, Jin Pyo Kang, Ho‐Sung Lee, Ik‐Hyeon Jeon, Ki‐Ju Park, Won‐Ju Cho, Seung‐heon Chris Baek, Joo‐Hyung Chae, Hamin Park   +8 more
wiley   +1 more source

Computational investigation for exploring botanical ingredients as potential negative allosteric modulators targeting metabotropic glutamate receptor 5. [PDF]

Res Pharm Sci
Singh P, Patra J, Saeedan AS, Aldossary SA, Ansari MN.   +4 more
europepmc   +1 more source

Lehr- und Übungsbuch für die Rechner HP-29C/HP-19C und HP-67/HP-97 [PDF]

, 1981
openaire   +1 more source

High Upper Critical Field and Type II Superconductivity in Epitaxial Cubic W2N Thin Films

Advanced Science, EarlyView.
Superconducting thin films of stoichiometric W2N demonstrate a high upper critical field (Hc2) of ∼ 8.5 T, uncommon among binary transition metal nitrides. This robust superconducting response under high magnetic fields highlights the technological relevance of W2N for superconducting applications, e.g., integrated quantum and cryogenic electronics ...
Aditya Singh, Arnaud le Febvrier, Sanath Kumar Honnali, Abhisek Mishra, Grzegorz Greczynski, Subhankar Bedanta, Per Eklund, Ajay Soni   +7 more
wiley   +1 more source

Home Parenteral Support in Severe Gitelman Syndrome: A Case Report. [PDF]

Clin Case Rep
Martin G, Fahal I, Mehta S.
europepmc   +1 more source

Probing the Energy Landscape of α‐Synuclein Amyloid Fibril Formation by Systematic K‐to‐Q Mutagenesis

Advanced Science, EarlyView.
We use lysine‐to‐glutamine mutations to study the effect of electrostatics on the kinetics and thermodynamics of alpha‐synuclein amyloid fibril formation. We find that mutational effects map on their structural context within fibrils and identify residues that modulate the energy landscape of alpha‐synuclein self‐assembly. Our work outlines a scalable,
Antonin Kunka, Azad Farzadfard, Jacob Aunstrup Larsen, Rasmus Krogh Norrild, Federica Saraceno, Celia Fricke, Hossein Mohammad‐Beigi, Ahmed Sadek, Jonas Folke, Susana Aznar, Alexander K. Buell   +10 more
wiley   +1 more source

Early Genotype-Driven Diagnosis of Hermansky-Pudlak Syndrome Type 4 in a Child With Oculocutaneous Albinism: An Ophthalmic Case Report. [PDF]

Cureus
Szabo D, Waldispühl-Geigl J, Kamper S, Pilch H, Plecko B, Vollnhofer K, Posch-Pertl L.   +6 more
europepmc   +1 more source