Results 171 to 180 of about 74,087 (340)

Kinesin‐Induced Buckling Reveals the Limits of Microtubule Self‐Repair

Advanced Science, EarlyView.
This study shows that kinesin‐driven buckling induces extensive microtubule lattice damage that often exceeds intrinsic self‐repair and leads to filament failure. While curvature, motor motility, and force individually cause limited damage, their combination overwhelms repair.
Shweta Nandakumar, Jonas Bosche, Mirko Wieczorek, Constantin Matteo Albrecht, Belinda König, Mona Grünewald, Ludger Santen, Stefan Diez, Reza Shaebani, Laura Schaedel   +9 more
wiley   +1 more source

Proposed taxonomic split of the Peromyscus maniculatus species complex. The proposed split [25,26] divides P. maniculatus into four new species as recognized by the Mammal Diversity Database [3]. Note that the name P. maniculatus sensu stricto applies east of the Mississippi River in the U.S. and P. sonoriensis applies to most of the Southwest where the initial outbreak of HPS was first detected. Base map layer from OpenStreetMap under the Open Database License.

Ally Finkbeiner (21519983), Ahmad Khatib (21519986), Nathan Upham (5771495), Beckett Sterner (21519989)   +3 more
openalex   +1 more source

Genetic variants and phylogenetic analysis of <i>Haemophilus parasuis</i> (HPS) <i>OMPP2</i> detected in Sichuan, China from 2013 to 2015

, 2017
Xulong Wu, Lu Xiao, Yin Wang, Xueping Yao, Zexiao Yang   +4 more
openalex   +2 more sources

Hemophagocytic syndrome caused by Epstein-Barr virus and cytomegalovirus infection during neoadjuvant chemoradiotherapy for rectal cancer: a case report. [PDF]

Front Med (Lausanne)
Kanesada K, Yoshimatsu K, Yano S, Higashida M, Okada T, Endo S, Fujiwara Y, Ueno T.   +7 more
europepmc   +1 more source

Deep Brain Stimulation Induces Antidepressant Effects by Restoring High‐Fidelity Communication in the BNST‐NAc Circuit

Advanced Science, EarlyView.
This cross‐species study reveals that pathological hyperactivity of BNST neurons in depressive states disrupts inhibitory period and isolated spikes in the BNST‐NAc circuit. DBS achieves its antidepressant effects by precisely restoring network inhibitory periods and high‐fidelity signal transmission.
Xin Lv, Yu Cao, Yuhan Wang, Yunhao Wu, Yingying Zhang, Kuanghao Ye, Xian Qiu, Qingfang Sun, Liuguan Bian, Halimureti Paerhati, Valerie Voon, Shikun Zhan, Bomin Sun   +12 more
wiley   +1 more source

Safety, efficacy and outcomes of the new GreenLight XPS 180W laser system compared to the GreenLight HPS 120W system for the treatment of benign prostatic hyperplasia in a prospective nonrandomized single-centre study

, 2015
Alper Eken, Bülent Soyupak, Meltem Açıl, Taner Arpacı, Tuğana Akbaş   +4 more
openalex   +2 more sources

Does Clinical Training Influence Empathy in Dental Students? Evidence from a Cross-Sectional Study in Lithuania. [PDF]

Dent J (Basel)
Rogalnikovaitė K, Narbutaitė J, Andruškevičienė V, Brukienė V, Bendoraitienė EA.   +4 more
europepmc   +1 more source

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

Advanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma, Xing Li, Minxuan Jing, Zezhong Yang, Jiale He, Jianpeng Li, Xiao Liang, Yunzhong Jiang, Rou Huang, Yuanquan Zhang, Yuanchun Pu, Jiawei Xiu, Yutong Chen, Kaibo Mi, Pu Zhang, Lei Wang, Jinhai Fan   +16 more
wiley   +1 more source

Structural Characterization and Functional Annotation of Hypothetical Proteins in the Multidrug-Resistant Strains of <i>Pseudomonas aeruginosa</i>. [PDF]

Biomed Res Int
Khoonsari FN, Zafari Z.
europepmc   +1 more source

PEC‐DFM Hybrid‐Sensor Based on Nanoparticle‐Resolved Estimation for Sensitive and Reversible Glucose Monitoring

Advanced Science, EarlyView.
Abstract The accurate detection of glucose in wound exudate is critically important for monitoring chronic wound healing. While photoelectrochemical (PEC) sensors are widely used, they often suffer from material degradation caused by redox reactions during operation. Herein, we introduce a dark‐field microscopy (DFM) setup integrated with a PEC system,
Zihao Zhang, Junzheng Liu, Qinggong Wu, Yuan Zeng, Gang Xiao, Zhao Yue, Zhigang Zang, Shuang Zhao   +7 more
wiley   +1 more source