Predicting Different Recurrence Risk in HNSCC Using Circulating Inflammatory and T‐Cell Biomarkers
ABSTRACT Objective Head and neck squamous cell carcinoma (HNSCC) lacks reliable prognostic circulating biomarkers, and the role of the immune system in its progression remains incompletely understood. This study aimed to evaluate the prognostic value of systemic inflammatory and immune biomarkers in surgically treated patients with primary oral cavity (
Riccardo Gili +10 more
wiley +1 more source
ABSTRACT Objective With regulatory approval of HPV‐specific immunotherapy for recurrent respiratory papillomatosis (RRP) and growing experience with systemic bevacizumab, a management algorithm incorporating these medical treatments is warranted. Data Sources and Methods RRP Foundation (RRPF) Key Opinion Leaders offer a proposed management algorithm ...
Simon R. Best +17 more
wiley +1 more source
The Patient Perspective of Living With Recurrent Respiratory Papillomatosis
This study was conducted to better understand the perspectives and real‐world impact of the disease burden on patients diagnosed with recurrent respiratory papillomatosis (RRP) and caregivers who experience the disease daily. RRP results in clinical, financial, and psychosocial burdens. Increased public awareness of human papillomavirus (HPV) infection
Sara I. Pai +7 more
wiley +1 more source
Distribution of HPV genotypes and comparison of cervico-vaginal cytologies in PCR-detected HPV-positive patients: a retrospective observational study. [PDF]
Duran MN +4 more
europepmc +1 more source
ABSTRACT Background Vulvar lichen simplex chronicus (VLSC) is a chronic inflammatory dermatosis that remains difficult to manage long term. Fractional CO2 laser (FxCO2) combined with topical corticosteroids (TCs) has emerged as a potential therapeutic strategy; however, high‐quality long‐term evidence remains limited.
Dongmei Wei +6 more
wiley +1 more source
HPV testing with 16/18 genotyping for risk stratification among women with normal cytology: a multicenter prospective cohort study from China. [PDF]
Zhang J +9 more
europepmc +1 more source
Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik +3 more
wiley +1 more source
Efficient information extraction using LLMs and knowledge distillation: A study on HPV health communication. [PDF]
Khan SH, Lybarger K.
europepmc +1 more source
Prevalence of Gardnerella vaginalis in HR HPV-positive women and its association with squamous intraepithelial lesions. [PDF]
Serafini A +4 more
europepmc +1 more source
CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li +8 more
wiley +1 more source

