Results 211 to 220 of about 74,023 (261)

Socioeconomic Risk Factors for Incomplete Vaccination in Swedish Two‐Year‐Olds—A Nationwide, Population‐Based Cohort Study

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim To analyse the association between specific socioeconomic measures and the risk of incomplete vaccination for diphtheria‐tetanus‐pertussis (DTP) and measles‐containing vaccine (MCV) in Swedish two‐year‐olds. Methods This nationwide, population‐based cohort study included 227 457 children born in Sweden during 2014–2015.
Cecilia Chrapkowska Almqvist   +5 more
wiley   +1 more source

The Australian Penile Cancer Clinical Registry: a comprehensive national approach to data collection

open access: yesBJU International, EarlyView.
Background Penile cancer is a rare malignancy, with an Australian incidence of 0.6 in 100 000 men, with a wide range of clinical presentations, from localised, curable tumours to aggressive forms with high morbidity and mortality. Epidemiological data and management guidelines for penile cancer in Australia are limited.
Henry Y.C. Pan   +11 more
wiley   +1 more source

Diagnosis of penile cancer with ex vivo fluorescence confocal microscopy using the Histolog® Scanner

open access: yesBJU International, EarlyView.
Objectives To evaluate the feasibility and diagnostic performance of ex vivo fluorescence confocal microscopy (FCM) using the Histolog® Scanner (SamanTree Medical SA, Lausanne, Switzerland) for the assessment of penile cancer (PeCa) specimens, and to compare FCM‐based diagnoses with standard formalin‐fixed, paraffin‐embedded (FFPE) histopathology ...
Xiaohu Zhang   +8 more
wiley   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

open access: yesBritish Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu   +6 more
wiley   +1 more source

HPV and HPV-Associated Diseases

Infectious Disease Clinics of North America, 2013
Human papillomavirus (HPV) is the most common sexually transmitted infection. HPV is associated with a significant burden of disease and cancer, including anogenital warts and recurrent respiratory papillomatosis, and anogenital and oropharyngeal cancers.
Eileen F Dunne
exaly   +3 more sources

Circulating HPV DNA in HPV-associated cancers

Clinica Chimica Acta, 2023
Human papillomavirus (HPV) infections are the primary cause of almost all cervical cancers, anal cancers, and a variable proportion of other anogenital tumors, as well as head and neck cancers. Circulating HPV DNA (cHPV-DNA) is emerging as a biomarker with extensive potential in the management of HPV-driven malignancies.
Guigao Lin, Jinming Li
openaire   +2 more sources

Immunobiology of HPV and HPV vaccines

Gynecologic Oncology, 2008
Genital human papillomavirus (HPV) infection with both low- and high-risk types is common, but most infections resolve as a result of a cell-mediated immune response. Failure to induce an effective immune response is related to inefficient activation of innate immunity and ineffective priming of the adaptive immune response; this defective immune ...
openaire   +2 more sources

Detection of HPV-20, HPV-23, and HPV-DL332 in a solitary eyelid syringoma

American Journal of Ophthalmology, 2000
To report evidence of many human papillomavirus types occurring in a solitary syringoma clinically appearing as a papilloma.A 57-year-old man presented with a 10-year history of an upper eyelid tumor. Histopathology, human papillomavirus-nested polymerase chain reaction, human papillomavirus-DNA cloning into vector pCR2.1, sequencing, and computer ...
A, Assadoullina   +3 more
openaire   +2 more sources

HPV vaccines

Best Practice & Research Clinical Obstetrics & Gynaecology, 2006
The ability to generate human papillomavirus virus (HPV)-like particles by the synthesis and self-assembly in vitro of the major virus capsid protein L1 has transformed our prospects for preventing cervical carcinoma in women. These particles provide vaccines that are immunogenic and safe, and data from proof-of-principle efficacy trials strongly ...
openaire   +2 more sources

Preclinical models of HPV+ and HPV− HNSCC in mice: An immune clearance of HPV+ HNSCC

Head & Neck, 2009
AbstractBackground.To investigate whether human papilloma virus (HPV)‐specific immune mechanisms can result in tumor clearance, we have created HPV+ and HPV− tonsil cells that form squamous cancers in immune‐competent mice. Here, we determine that an immune‐specific response can clear HPV+ tumor cells and the cellular requirements to mediate this tumor
Robin, Williams   +5 more
openaire   +2 more sources

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