Results 81 to 90 of about 291,345 (345)

In Situ Vaccines in the Era of Cancer Immunotherapy: Conceptual Innovation and Clinical Translation

Advanced Science, EarlyView.
In this review, the basic concepts of in situ vaccination are discussed, its advantages over conventional vaccines, and key historical milestones, from the first use of Coley's toxins to the most recent FDA‐approved in situ vaccine for bladder cancer.
Yiru Shi, Yuxuan Hou, Moustafa T. Mabrouk, Chengzhong Yu, Yannan Yang   +4 more
wiley   +1 more source

Activation of Akt at T308 and S473 in alcohol, tobacco and HPV-induced HNSCC:is there evidence to support a prognostic or diagnostic role? [PDF]

, 2014
BACKGROUND: Tobacco, alcohol and HPV infection are associated with increased risk of HNSCC. However, little is known about the underlying signaling events influencing risk.
Cochrane, Lynda, Ellis, Ian R., Islam, Mohammad R., Jones, Sarah J., Macluskey, Michaelina   +4 more
core   +2 more sources

A new approach for detecting HPV DNA in cervical swabs: comparison of nucleic acid extraction with direct PCR

Virology Journal
Background Almost all cases of cervical cancer are associated with persistent high-risk HPV infection. WHO prioritizes primary HPV testing for cervical cancer screening.
Fatih Çubuk, Muhammet Çağrı Yıldız, Fikrican Balcı, Ahmet İrgin, Savaş Aşkın, Ekrem Sağtaş, Sedat kaygusuz   +6 more
doaj   +1 more source

Bronquiectasias

Revista Portuguesa de Pneumologia, 1999
RESUMO: As bronquiectasias, outrora frequentes, têm vindo a tomarse numa situação patológia comparativamente rara. No entanto, a sua importância clínica motivou os autores a realizarem uma revisão teórica sobre este tema, na qual procuram abordar a ...
Vicència Ribeiro, Filipe Froes
doaj   +1 more source

HPV vaccination bridges to HPV screening [PDF]

EClinicalMedicine, 2020
Diane M. Harper, Sherri Sheinfeld Gorin
openaire   +3 more sources

CDK4/6 Inhibitor Priming Enhances PD‐1 Blockade via Sellhi Neutrophil‐Induced Stat5a+ Progenitor Exhausted CD8+ T Cell

Advanced Science, EarlyView.
Activated tumor‐intrinsic cyclin D1‐CDK4/6 signaling attenuates lymphocyte infiltration, and consequently, and immunotherapy resistance in HNSCC. It is discovered that brief CDK4/6i priming before anti‐PD‐1 results in enhanced durability of ICB response durability through Stat5a+ progenitor exhausted CD8+ T cells induced by IL15‐secreted Sell(hi ...
Yu Zhang, Bao Sun, Rong Zhou, Zizhen Gong, Yong Han, Wenjie Tao, Chaoji Shi, Wuchang Zhang, Laikui Liu, Zhiyuan Zhang, Jiang Li, Qi Zhu, Weiwen Zhu, Ziyue Gu   +13 more
wiley   +1 more source

Human Pappilomavirus Genotype in Cervical Tissue of Patients with Cervical Intraepithelial Neoplasia (CIN) 1, CIN 2, and CIN 3 [PDF]

, 2016
Objectives: to determine the genotype of HPV in patients with precancerous lesions of cervical tissue.Materials and Methods: An observational study with cross sectional study of patients paraffin block CIN1, CIN2, CIN3 was conducted in Dr Soetomo ...
Alia, R. (Rahmi), I’tishom, R. (Renny), Mastutik, G. (Gondo), Rahaju, A. S. (Anny), Rahniayu, A. (Alphania)   +4 more
core   +1 more source

Assessing HPV vaccine coverage in Australia by geography and socioeconomic status: are we protecting those most at risk?

Australian and New Zealand Journal of Public Health, 2014
Objective: To determine whether HPV vaccine coverage in 12–13‐year‐olds varies by geographical area, remoteness and ecological level indicators of socioeconomic status (SES).
Bianca Barbaro, Julia M.L. Brotherton
doaj   +1 more source

Avaliação da dispneia e padrões ventilatórios num grupo de doentes com limitação crónica do débito aéreo candidatos a um programa de reabilitação** Comunicação apresentada na Mesa Redonda Reabilitação do Doente Respiratório – Conceitos Actuais”; VIII CongTesso da SPPR – Póvoa de Varzim 1992.

Revista Portuguesa de Pneumologia, 1995
RESUMO: Com o objectivo de monitorizar doentes sujeitos a Programas de Reabilitação Respiratória (PRR) os autores elaboraram urn protocolo de exploração funcional respiratória, mediante o recurso a técnicas de avaliação do controlo da ventilaçã
Miguel Mota Carmo, Bárbara Cristina, Paulo Roxo Neves, Jaime Branco, Maria Camila Canteiro, António Bensabat Rendas   +5 more
doaj   +1 more source

Targeting of the CD161 Inhibitory Receptor Enhances Bone‐Marrow‐Resident Memory CD8+ T‐Cell‐Mediated Immunity against Multiple Myeloma

Advanced Science, EarlyView.
CD161 is identified as a novel inhibitory receptor on bone marrow (BM)‐resident CD8⁺ T cells in multiple myeloma (MM). Through interaction with its ligand CLEC2D, CD161 impairs T‐cell function and promotes immune suppression. Blockade of CD161 restores tissue residency and cytotoxicity of CD8⁺ T cells and enhances chimeric antigen receptor T‐cell (CAR ...
Liwen Wang, Linzhi Xie, Yi Zhou, Shiming Tan, Yan Yu, Qin Zhang, Xuefeng Chen, Yuhan Yan, Ruiheng Luo, Han Xiao, Qian Cheng, Jian Zhang, Ying Li, Erhua Wang, Tiebin Jiang, Jing Liu, Xin Li   +16 more
wiley   +1 more source