Results 91 to 100 of about 373,022 (151)

Wrist Bone Erosion Burden Assessed by HR-pQCT is Associated with Functional Disability in Patients with Rheumatoid Arthritis

Journal of Clinical Rheumatology and Immunology
Objective: To determine whether wrist bone erosive burden assessed by high-resolution peripheral quantitative computed tomography (HR-pQCT) is associated with functional disability in patients with rheumatoid arthritis (RA).
Xianfeng Yan, Yingzhao Jin, Isaac T Cheng, Ho So, Yan Kitty Kwok, Yan Ling Kwok, Jackson KY Chan, Ruby TY Chan, Carson CY Yip, Vivian Hung, Sheung-Wai Law, Jack JW Lee, James F Griffith, Ling Qin, Lai-Shan Tam   +14 more
doaj   +1 more source

Effects of achieving simple disease activity index remission on joint space outcomes progression in early rheumatoid arthritis: an exploratory study using high-resolution peripheral quantitative computed tomography

Therapeutic Advances in Musculoskeletal Disease
Background: Rheumatoid arthritis is a chronic inflammatory disease with progressive joint destruction resulting in functional loss. High-resolution peripheral quantitative CT (HR-pQCT) is a novel technique for detailed volumetric assessment of joint ...
Qihan Wu, Ho So, Isaac T. Cheng, Yingzhao Jin, Sze-Lok Lau, Tin-Yuet Chan, Evelyn Chow, Ling Qin, Vivian W. Hung, James F Griffith, Kitty Kwok, Isaac Yim, Shirley Ying, Ka Lai Violet Lee, Jack J. W. Lee, Lai-Shan Tam   +15 more
doaj   +1 more source

Comparative study of the inhibitory effect on bone erosion progression with denosumab treatment and conventional treatment in rheumatoid arthritis patients: study protocol for an open-label randomized controlled trial by HR-pQCT

Trials, 2019
Background Rheumatoid arthritis (RA) is a chronic inflammatory disease of the joints, causes joint destruction, and leads to physical disability. Advances in the treatment of RA, such as biologic disease-modifying anti-rheumatic drugs (DMARDs), have ...
Naoki Iwamoto, Shuntaro Sato, Remi Sumiyoshi, Ko Chiba, Nanami Miyamoto, Kumiko Arinaga, Makiko Kobayashi, Hiroshi Yamamoto, Makoto Osaki, Atsushi Kawakami   +9 more
doaj   +1 more source

Deep Convolutional Neural Networks Provide Motion Grading for High-Resolution Peripheral Quantitative Computed Tomography of the Scaphoid

Diagnostics
In vivo high-resolution peripheral quantitative computed tomography (HR-pQCT) studies on bone characteristics are limited, partly due to the lack of standardized and objective techniques to describe motion artifacts responsible for lower-quality images ...
Stefan Benedikt, Philipp Zelger, Lukas Horling, Kerstin Stock, Johannes Pallua, Michael Schirmer, Gerald Degenhart, Alexander Ruzicka, Rohit Arora   +8 more
doaj   +1 more source

Three-dimensional HR-pQCT image of the distal radius with crosscut showing the trabecular bone.

, 2014
Three-dimensional HR-pQCT image of the distal radius with crosscut showing the trabecular bone.
Simon K. M. Lee (587377), Zhen Liu (74646), Yong Qiu (83780), Fiona W. P. Yu (587373), King Lok Liu (587375), Vivian W. Y. Hung (587374), Elisa M. S. Tam (587372), Bobby K. W. Ng (587376), Jack C. Y. Cheng (500528), Tsz-Ping Lam (3145017)   +9 more
core   +1 more source

Assessing bone microstructure at the distal radius in children and adolescents using HR-pQCT: A methodological pilot study

, 2010
We examined the use of high-resolution peripheral quantitative computed tomography (HR-pQCT [XtremeCT; Scanco Medical, Switzerland]) to assess bone microstructure at the distal radius in growing children and adolescents.

core   +1 more source

Fabric–elasticity relationships of femoral head trabecular bone are similar in Type 2 diabetes and non-diabetic individuals

Bone Reports
Type 2 diabetes (T2D) is a chronic disease leading to an elevated glucose level in the blood and increased fracture risk. Because T2D individuals tend to have normal to higher areal bone mineral density (aBMD) than healthy individuals, their fracture ...
Mathieu Simon, Sasidhar Uppuganti, Jeffry S. Nyman, Philippe Zysset   +3 more
doaj   +1 more source

Homogenized finite element analysis of distal tibia sections: Achievements and limitations

Bone Reports
High-resolution peripheral quantitative computed tomography (HR-pQCT) based micro-finite element (μFE) analysis allows accurate prediction of stiffness and ultimate load of standardised (∼1 cm) distal radius and tibia sections. An alternative homogenized
Mathieu Simon, Michael Indermaur, Denis Schenk, Benjamin Voumard, Ivan Zderic, Dominic Mischler, Michael Pretterklieber, Philippe Zysset   +7 more
doaj   +1 more source

Bone mineral density assessment by DXA in disease-associated osteoporosis: the limitations

Frontiers in Endocrinology
Measuring bone density by DXA is a routine means of predicting fracture risk. These 2–dimensional images have limitations and may underestimate the risk of fracture due to inadequate evaluation of bone strength.
Kamyar Asadipooya, Loren Wissner Greene
doaj   +1 more source

High-resolution peripheral quantitative computed tomography (HR-pQCT) to detect compartmental bone loss on androgen deprivation therapy (ADT): A feasibility study.

, 2017
209 Background: ADT causes bone loss, yet standard bone density (DXA) measurements do not distinguish cortical vs. trabecular bone loss and are falsely elevated in patients (pts) with sclerotic metastases, potentially underestimating fracture risk.
Rahul Raj Aggarwal, Brian Ma, Tammy J. Rodvelt, Jeffrey Hough, Miles Thomas, Sharmila Majumdar, Dora Tao, Li Zhang   +7 more
core   +1 more source